STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEG59189.1Diguanylate cyclase; SMART: GGDEF domain containing protein; TIGRFAM: diguanylate cyclase; KEGG: drm:Dred_2700 diguanylate cyclase; PFAM: GGDEF domain containing protein. (407 aa)    
Predicted Functional Partners:
AEG59916.1
TIGRFAM: PAS sensor protein; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold-4 domain protein; PAS fold domain protein; response regulator receiver; Hpt domain protein; KEGG: drm:Dred_2145 multi-sensor hybrid histidine kinase; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS domain containing protein; response regulator receiver.
 
 0.991
AEG61336.1
TIGRFAM: PAS sensor protein; PFAM: ATP-binding region ATPase domain protein; PAS fold domain protein; response regulator receiver; GAF domain protein; histidine kinase A domain protein; KEGG: dae:Dtox_0050 PAS/PAC sensor signal transduction histidine kinase; SMART: ATP-binding region ATPase domain protein; response regulator receiver; PAS domain containing protein; PAC repeat-containing protein; GAF domain protein; histidine kinase A domain protein.
 
 
 0.954
AEG60897.1
TIGRFAM: diguanylate cyclase; PAS sensor protein; PFAM: EAL domain protein; GGDEF domain containing protein; GAF domain protein; histidine kinase HAMP region domain protein; PAS fold-4 domain protein; KEGG: drm:Dred_1346 diguanylate cyclase/phosphodiesterase with PAS/PAC and GAF sensor(s); SMART: EAL domain protein; GGDEF domain containing protein; GAF domain protein; histidine kinase HAMP region domain protein; PAS domain containing protein.
 
 
0.863
AEG58769.1
TIGRFAM: PAS sensor protein; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold domain protein; KEGG: drm:Dred_1269 signal transduction histidine kinase, nitrogen specific, NtrB; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS domain containing protein; PAC repeat-containing protein.
  
 
 0.842
AEG58967.1
EAL domain protein; KEGG: drm:Dred_0836 diguanylate phosphodiesterase; PFAM: EAL domain protein; SMART: EAL domain protein.
 
 
 0.833
AEG58317.1
KEGG: drm:Dred_0009 metal dependent phosphohydrolase; PFAM: metal-dependent phosphohydrolase HD sub domain; SMART: metal-dependent phosphohydrolase HD region.
  
 0.821
AEG58374.1
KEGG: acl:ACL_0673 metal dependent phosphohydrolase; PFAM: metal-dependent phosphohydrolase HD sub domain; SMART: metal-dependent phosphohydrolase HD region.
 
   
 0.808
AEG61498.1
KEGG: dae:Dtox_2730 histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein.
  
 
 0.790
AEG58652.1
KEGG: drm:Dred_0279 metal dependent phosphohydrolase; PFAM: metal-dependent phosphohydrolase HD sub domain; GAF domain protein; SMART: metal-dependent phosphohydrolase HD region; GAF domain protein.
  
 0.786
AEG60726.1
EAL domain protein; KEGG: pth:PTH_0666 signaling protein; PFAM: EAL domain protein; SMART: EAL domain protein.
 
 
 0.766
Your Current Organism:
Desulfotomaculum ruminis
NCBI taxonomy Id: 696281
Other names: D. ruminis DSM 2154, Desulfotomaculum ruminis ATCC 23193, Desulfotomaculum ruminis DL, Desulfotomaculum ruminis DSM 2154, Desulfotomaculum ruminis str. DSM 2154, Desulfotomaculum ruminis strain DSM 2154
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.