STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEG59199.1N-acetylmuramoyl-L-alanine amidase; PFAM: cell wall hydrolase/autolysin; SH3 type 3 domain protein; KEGG: drm:Dred_2693 N-acetylmuramoyl-L-alanine amidase; SMART: cell wall hydrolase/autolysin; SH3 domain protein. (591 aa)    
Predicted Functional Partners:
AEG59198.1
PFAM: ErfK/YbiS/YcfS/YnhG family protein; Peptidoglycan-binding domain 1 protein; KEGG: drm:Dred_2694 ErfK/YbiS/YcfS/YnhG family protein.
     
 0.833
AEG61988.1
PFAM: Peptidase M23; Lytic transglycosylase catalytic; KEGG: drm:Dred_0935 peptidase M23B.
 
   
 0.698
AEG61558.1
SMART: PASTA domain containing protein; TIGRFAM: stage V sporulation protein D; KEGG: drm:Dred_0669 stage V sporulation protein D; PFAM: penicillin-binding protein transpeptidase; Penicillin-binding protein dimerisation domain; PASTA domain containing protein.
 
  
 0.651
AEG58461.1
KEGG: drm:Dred_0093 ErfK/YbiS/YcfS/YnhG family protein; PFAM: ErfK/YbiS/YcfS/YnhG family protein; Peptidoglycan-binding lysin domain; SMART: Peptidoglycan-binding LysM.
     
 0.627
AEG59209.1
Non-canonical purine NTP pyrophosphatase, rdgB/HAM1 family; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.
 
     0.617
cinA
Competence/damage-inducible protein CinA; KEGG: drm:Dred_1922 competence damage-inducible protein A; TIGRFAM: competence/damage-inducible protein CinA; PFAM: CinA domain protein; molybdopterin binding domain; Belongs to the CinA family.
 
     0.616
cinA-2
Competence/damage-inducible protein CinA; KEGG: cno:NT01CX_0942 competence damage-inducible protein A; TIGRFAM: competence/damage-inducible protein CinA; PFAM: CinA domain protein; molybdopterin binding domain; Belongs to the CinA family.
 
     0.587
rph
Ribonuclease PH; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.
       0.566
AEG59206.1
KEGG: drm:Dred_2686 beta-lactamase domain-containing protein.
 
 
   0.557
AEG61188.1
CBS domain containing protein; KEGG: drm:Dred_1131 polynucleotide adenylyltransferase region; PFAM: CBS domain containing protein; phosphoesterase RecJ domain protein; phosphoesterase DHHA1; Polynucleotide adenylyltransferase region; SMART: CBS domain containing protein; Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.
  
 
 0.545
Your Current Organism:
Desulfotomaculum ruminis
NCBI taxonomy Id: 696281
Other names: D. ruminis DSM 2154, Desulfotomaculum ruminis ATCC 23193, Desulfotomaculum ruminis DL, Desulfotomaculum ruminis DSM 2154, Desulfotomaculum ruminis str. DSM 2154, Desulfotomaculum ruminis strain DSM 2154
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.