STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEG59258.1PFAM: metallophosphoesterase; KEGG: drm:Dred_2571 metallophosphoesterase. (455 aa)    
Predicted Functional Partners:
AEG59259.1
PFAM: SMC domain protein; KEGG: drm:Dred_2570 SMC domain-containing protein.
 
 0.999
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
  
 0.996
AEG61783.1
KEGG: thx:Thet_1684 hypothetical protein.
  
 0.989
AEG58637.1
TIGRFAM: ATP-dependent DNA helicase RecQ; ATP-dependent DNA helicase, RecQ family; PFAM: RQC domain; DEAD/DEAH box helicase domain protein; helicase domain protein; HRDC domain protein; KEGG: drm:Dred_1261 ATP-dependent DNA helicase RecQ; SMART: DEAD-like helicase; helicase domain protein; HRDC domain protein.
  
 0.933
dinG
DNA polymerase III, epsilon subunit; 3'-5' exonuclease.
  
 0.927
AEG58855.1
PFAM: Ankyrin; KEGG: spu:585023 similar to NACHT domain protein, putative.
    
 0.866
AEG60119.1
PFAM: sulphate transporter; Sulfate transporter/antisigma-factor antagonist STAS; KEGG: drm:Dred_1995 sulphate transporter.
  
   0.825
AEG60113.1
KEGG: drm:Dred_2002 ATP dependent DNA ligase; TIGRFAM: DNA polymerase LigD, ligase domain protein; PFAM: ATP dependent DNA ligase; ATP dependent DNA ligase domain protein.
   
 0.799
recA
recA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family.
  
 0.771
AEG60058.1
PFAM: AAA-4 family protein; KEGG: drm:Dred_2059 putative transcriptional regulator.
  
     0.732
Your Current Organism:
Desulfotomaculum ruminis
NCBI taxonomy Id: 696281
Other names: D. ruminis DSM 2154, Desulfotomaculum ruminis ATCC 23193, Desulfotomaculum ruminis DL, Desulfotomaculum ruminis DSM 2154, Desulfotomaculum ruminis str. DSM 2154, Desulfotomaculum ruminis strain DSM 2154
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