STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEG59282.1SMART: AAA ATPase; TIGRFAM: ATP-dependent protease LonB; KEGG: drm:Dred_2560 ATPase central domain-containing protein; PFAM: AAA ATPase central domain protein. (570 aa)    
Predicted Functional Partners:
lon
ATP-dependent protease La; ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short- lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
  
  
0.715
AEG61300.1
KEGG: drm:Dred_1057 stage III sporulation protein SpoAB; TIGRFAM: stage III sporulation protein AB; PFAM: Sporulation stage III protein AB.
  
    0.680
engB
Ribosome biogenesis GTP-binding protein YsxC; Necessary for normal cell division and for the maintenance of normal septation; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
       0.666
AEG61248.1
KEGG: drm:Dred_1095 hypothetical protein; TIGRFAM: stage II sporulation protein M; PFAM: protein of unknown function DUF95 transmembrane.
  
    0.607
clpX
ATP-dependent Clp protease, ATP-binding subunit ClpX; ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
  
  
 0.585
AEG61298.1
TIGRFAM: stage III sporulation protein AD; KEGG: drm:Dred_1059 putative sporulation protein.
  
    0.557
AEG61297.1
KEGG: drm:Dred_1060 hypothetical protein; TIGRFAM: stage III sporulation protein AE; PFAM: Sporulation stage III protein AE.
  
    0.545
AEG58312.1
KEGG: drm:Dred_0005 hypothetical protein.
  
     0.513
clpP
ATP-dependent Clp protease, proteolytic subunit ClpP; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family.
  
  
 0.480
AEG62088.1
Sporulation protein YyaC; KEGG: drm:Dred_3314 hypothetical protein; TIGRFAM: sporulation protein YyaC; PFAM: protein of unknown function DUF1256.
  
     0.467
Your Current Organism:
Desulfotomaculum ruminis
NCBI taxonomy Id: 696281
Other names: D. ruminis DSM 2154, Desulfotomaculum ruminis ATCC 23193, Desulfotomaculum ruminis DL, Desulfotomaculum ruminis DSM 2154, Desulfotomaculum ruminis str. DSM 2154, Desulfotomaculum ruminis strain DSM 2154
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