STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEG59706.1Manually curated; PFAM: Cupin 2 conserved barrel domain protein; helix-turn-helix domain protein; KEGG: tjr:TherJR_1682 transcriptional regulator, XRE family; SMART: helix-turn-helix domain protein. (185 aa)    
Predicted Functional Partners:
AEG59707.1
PFAM: AMP-dependent synthetase and ligase; KEGG: tjr:TherJR_1681 AMP-dependent synthetase and ligase.
 
 0.970
AEG60226.1
PFAM: AMP-dependent synthetase and ligase; KEGG: chy:CHY_0572 acetyl-coenzyme A synthetase family protein.
 
 0.728
guaA
GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP.
     
 0.659
AEG59332.1
PFAM: AMP-dependent synthetase and ligase; KEGG: pth:PTH_0838 acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II.
  
 0.640
AEG59916.1
TIGRFAM: PAS sensor protein; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold-4 domain protein; PAS fold domain protein; response regulator receiver; Hpt domain protein; KEGG: drm:Dred_2145 multi-sensor hybrid histidine kinase; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS domain containing protein; response regulator receiver.
     
 0.619
AEG58691.1
Helix-turn-helix domain protein; KEGG: bcl:ABC3304 transcriptional regulator; PFAM: helix-turn-helix domain protein; Cupin 2 conserved barrel domain protein; SMART: helix-turn-helix domain protein.
 
   
 0.587
AEG58392.1
Cyclic nucleotide-binding protein; KEGG: pth:PTH_2806 transcriptional regulator; PFAM: cyclic nucleotide-binding; sigma-54 factor interaction domain-containing protein; SMART: cyclic nucleotide-binding.
  
  
 0.568
AEG58759.1
KEGG: drm:Dred_2758 UbiC transcription regulator-associated domain-containing protein; PFAM: UbiC transcription regulator-associated domain-containing protein; regulatory protein GntR HTH; SMART: regulatory protein GntR HTH.
  
  
 0.536
AEG58867.1
KEGG: drm:Dred_2751 UbiC transcription regulator-associated domain-containing protein; PFAM: UbiC transcription regulator-associated domain-containing protein; regulatory protein GntR HTH; SMART: regulatory protein GntR HTH.
  
  
 0.536
AEG59901.1
KEGG: drm:Dred_2149 regulatory protein GntR, HTH; PFAM: regulatory protein GntR HTH; TrkA-C domain protein; SMART: regulatory protein GntR HTH.
  
  
 0.536
Your Current Organism:
Desulfotomaculum ruminis
NCBI taxonomy Id: 696281
Other names: D. ruminis DSM 2154, Desulfotomaculum ruminis ATCC 23193, Desulfotomaculum ruminis DL, Desulfotomaculum ruminis DSM 2154, Desulfotomaculum ruminis str. DSM 2154, Desulfotomaculum ruminis strain DSM 2154
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