STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEG60228.1PFAM: thiamine pyrophosphate TPP-binding domain-containing protein; thiamine pyrophosphate central domain-containing protein; KEGG: bbe:BBR47_22570 putative pyruvate dehydrogenase; Belongs to the TPP enzyme family. (536 aa)    
Predicted Functional Partners:
AEG58655.1
TIGRFAM: acetolactate synthase, small subunit; KEGG: drm:Dred_0282 acetolactate synthase 3 regulatory subunit; PFAM: Acetolactate synthase, small subunit-like; amino acid-binding ACT domain protein.
 
 0.985
AEG59017.1
KEGG: drm:Dred_2896 acetolactate synthase 3 regulatory subunit; TIGRFAM: acetolactate synthase, small subunit; PFAM: Acetolactate synthase, small subunit-like; amino acid-binding ACT domain protein.
 
 0.985
AEG59628.1
KEGG: drm:Dred_2312 pyruvate kinase; TIGRFAM: pyruvate kinase; PFAM: Pyruvate kinase barrel; Pyruvate kinase alpha/beta; PEP-utilising protein mobile region; Belongs to the pyruvate kinase family.
  
 0.940
AEG58880.1
PFAM: malic protein NAD-binding; malic protein domain protein; amino acid-binding ACT domain protein; KEGG: drm:Dred_2955 malate dehydrogenase.
  
 
 0.922
ackA
Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family.
    
 0.912
AEG58400.1
PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; KEGG: drm:Dred_0047 pyruvate flavodoxin/ferredoxin oxidoreductase domain-containing protein.
  
 
 0.907
AEG60522.1
PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; Transketolase domain-containing protein; KEGG: pth:PTH_0847 pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, alpha subunit.
  
 
 0.907
AEG61258.1
3-methyl-2-oxobutanoate dehydrogenase (ferredoxin); KEGG: adg:Adeg_1385 2-ketoisovalerate ferredoxin reductase; PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein.
  
 
 0.907
AEG58401.1
PFAM: thiamine pyrophosphate TPP-binding domain-containing protein; KEGG: drm:Dred_0048 thiamine pyrophosphate binding domain-containing protein.
  
 
 0.906
AEG60521.1
2-oxoglutarate synthase; KEGG: hmo:HM1_2763 2-oxoacid:ferredoxin oxidoreductase, beta subunit; PFAM: thiamine pyrophosphate TPP-binding domain-containing protein.
  
 
 0.906
Your Current Organism:
Desulfotomaculum ruminis
NCBI taxonomy Id: 696281
Other names: D. ruminis DSM 2154, Desulfotomaculum ruminis ATCC 23193, Desulfotomaculum ruminis DL, Desulfotomaculum ruminis DSM 2154, Desulfotomaculum ruminis str. DSM 2154, Desulfotomaculum ruminis strain DSM 2154
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