STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEG60237.1PFAM: histone deacetylase superfamily; KEGG: drm:Dred_1885 histone deacetylase superfamily protein. (451 aa)    
Predicted Functional Partners:
AEG60242.1
KEGG: drm:Dred_1880 ATPase central domain-containing protein; PFAM: AAA ATPase central domain protein; SMART: AAA ATPase.
 
 
 0.976
AEG60236.1
PFAM: Hydantoinase/oxoprolinase; Hydantoinaseoxoprolinase domain protein; KEGG: drm:Dred_1886 hydantoinase/oxoprolinase.
 
   0.954
htpG
Heat shock protein Hsp90-like protein; Molecular chaperone. Has ATPase activity.
    
 0.885
mutL
DNA mismatch repair protein MutL; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.
   
   0.871
AEG58855.1
PFAM: Ankyrin; KEGG: spu:585023 similar to NACHT domain protein, putative.
   
 0.867
AEG60239.1
PFAM: protein of unknown function DUF548; KEGG: drm:Dred_1883 hypothetical protein.
 
    0.866
miaA
tRNA delta(2)-isopentenylpyrophosphate transferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family.
  
    0.850
mutS
DNA mismatch repair protein MutS; This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.
   
 
 0.845
AEG58393.1
SMART: AAA ATPase; KEGG: drm:Dred_0041 phosphoribulokinase/uridine kinase.
   
 0.843
AEG60784.1
PFAM: Silent information regulator protein Sir2; KEGG: drm:Dred_2032 silent information regulator protein Sir2.
    
 0.831
Your Current Organism:
Desulfotomaculum ruminis
NCBI taxonomy Id: 696281
Other names: D. ruminis DSM 2154, Desulfotomaculum ruminis ATCC 23193, Desulfotomaculum ruminis DL, Desulfotomaculum ruminis DSM 2154, Desulfotomaculum ruminis str. DSM 2154, Desulfotomaculum ruminis strain DSM 2154
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