Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
AEG60246.1KEGG: drm:Dred_1876 hypothetical protein. (459 aa)    
Predicted Functional Partners:
AEG60247.1
KEGG: drm:Dred_1875 hypothetical protein.
     0.986
AEG59207.1
KEGG: drm:Dred_2685 hypothetical protein.
 
     0.769
AEG59203.1
TIGRFAM: methylaspartate ammonia-lyase; KEGG: drm:Dred_2689 methylaspartate ammonia-lyase; PFAM: methylaspartate ammonia-lyase.
 
     0.764
glmS-2
Methylaspartate mutase, S subunit; Catalyzes the carbon skeleton rearrangement of L-glutamate to L-threo-3-methylaspartate ((2S,3S)-3-methylaspartate).
 
   
 0.755
glmE
Methylaspartate mutase, E subunit; Catalyzes the carbon skeleton rearrangement of L-glutamate to L-threo-3-methylaspartate ((2S,3S)-3-methylaspartate).
 
     0.746
AEG59201.1
KEGG: drm:Dred_2691 glutamate mutase, MutL.
 
     0.668
AEG60248.1
Regulatory protein MerR; KEGG: drm:Dred_1874 MerR family transcriptional regulator; PFAM: regulatory protein MerR; SMART: regulatory protein MerR.
  
    0.471
AEG61292.1
acetyl-CoA carboxylase, biotin carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.
  
  
 0.455
thiM
Hydroxyethylthiazole kinase; Catalyzes the phosphorylation of the hydroxyl group of 4- methyl-5-beta-hydroxyethylthiazole (THZ); Belongs to the Thz kinase family.
       0.438
Your Current Organism:
Desulfotomaculum ruminis
NCBI taxonomy Id: 696281
Other names: D. ruminis DSM 2154, Desulfotomaculum ruminis ATCC 23193, Desulfotomaculum ruminis DL, Desulfotomaculum ruminis DSM 2154, Desulfotomaculum ruminis str. DSM 2154, Desulfotomaculum ruminis strain DSM 2154
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