Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AEG60251.1PFAM: nitrogen-fixing NifU domain protein; KEGG: ckr:CKR_3218 hypothetical protein. (134 aa)    
Predicted Functional Partners:
iscS
Cysteine desulfurase NifS; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.
 
 0.995
AEG58639.1
KEGG: drm:Dred_0266 cysteine desulfurase family protein; TIGRFAM: cysteine desulfurase family protein; PFAM: aminotransferase class V.
  
 
 0.965
AEG60252.1
PFAM: Dinitrogenase iron-molybdenum cofactor biosynthesis protein; KEGG: amt:Amet_1464 dinitrogenase iron-molybdenum cofactor biosynthesis protein.
  
  
 0.803
AEG60253.1
KEGG: dsy:DSY3440 hypothetical protein.
     
 0.788
AEG60254.1
KEGG: dhd:Dhaf_1984 cobyrinic acid ac-diamide synthase.
     
 0.788
AEG60250.1
PFAM: protein of unknown function DUF134; KEGG: dhd:Dhaf_1981 protein of unknown function DUF134; Belongs to the UPF0251 family.
       0.777
dnaK
Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.
  
 0.746
AEG58969.1
KEGG: adg:Adeg_0813 hypothetical protein.
  
 0.746
dnaK-2
Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.
  
 0.746
AEG61951.1
KEGG: tmt:Tmath_0071 StbA family protein.
  
 0.746
Your Current Organism:
Desulfotomaculum ruminis
NCBI taxonomy Id: 696281
Other names: D. ruminis DSM 2154, Desulfotomaculum ruminis ATCC 23193, Desulfotomaculum ruminis DL, Desulfotomaculum ruminis DSM 2154, Desulfotomaculum ruminis str. DSM 2154, Desulfotomaculum ruminis strain DSM 2154
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