Nodes:
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
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[Homology]
Score
AEG60265.1Response regulator receiver; KEGG: hmo:HM1_2078 transcriptional regulatory protein; PFAM: response regulator receiver; transcriptional regulator domain-containing protein; SMART: response regulator receiver. (235 aa)    
Predicted Functional Partners:
AEG61517.1
TIGRFAM: PAS sensor protein; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold domain protein; histidine kinase HAMP region domain protein; KEGG: drm:Dred_0708 multi-sensor signal transduction histidine kinase; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS domain containing protein; histidine kinase HAMP region domain protein.
 0.979
AEG59916.1
TIGRFAM: PAS sensor protein; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold-4 domain protein; PAS fold domain protein; response regulator receiver; Hpt domain protein; KEGG: drm:Dred_2145 multi-sensor hybrid histidine kinase; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS domain containing protein; response regulator receiver.
  
 
 0.929
AEG61336.1
TIGRFAM: PAS sensor protein; PFAM: ATP-binding region ATPase domain protein; PAS fold domain protein; response regulator receiver; GAF domain protein; histidine kinase A domain protein; KEGG: dae:Dtox_0050 PAS/PAC sensor signal transduction histidine kinase; SMART: ATP-binding region ATPase domain protein; response regulator receiver; PAS domain containing protein; PAC repeat-containing protein; GAF domain protein; histidine kinase A domain protein.
 
 
 0.905
AEG61518.1
Response regulator receiver; KEGG: drm:Dred_0707 two component transcriptional regulator; PFAM: response regulator receiver; transcriptional regulator domain-containing protein; SMART: response regulator receiver.
  
  
 
0.902
AEG61986.1
TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; KEGG: aae:aq_035 hypothetical protein; SMART: GGDEF domain containing protein.
 
 
    0.895
AEG58700.1
ATP-binding region ATPase domain protein; KEGG: gct:GC56T3_1122 integral membrane sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein.
 
 
 0.827
AEG61498.1
KEGG: dae:Dtox_2730 histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein.
 
 0.813
AEG59053.1
ATP-binding region ATPase domain protein; KEGG: gym:GYMC10_3131 integral membrane sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein.
 
 
 0.801
AEG59472.1
TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; KEGG: gbm:Gbem_1202 diguanylate cyclase; SMART: GGDEF domain containing protein; GAF domain protein.
 
 
    0.796
AEG58783.1
ATP-binding region ATPase domain protein; KEGG: drm:Dred_2980 integral membrane sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein.
 
 0.787
Your Current Organism:
Desulfotomaculum ruminis
NCBI taxonomy Id: 696281
Other names: D. ruminis DSM 2154, Desulfotomaculum ruminis ATCC 23193, Desulfotomaculum ruminis DL, Desulfotomaculum ruminis DSM 2154, Desulfotomaculum ruminis str. DSM 2154, Desulfotomaculum ruminis strain DSM 2154
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