Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AEG60274.1PAS sensor protein; KEGG: drm:Dred_1863 putative PAS/PAC sensor protein; TIGRFAM: PAS sensor protein; PFAM: ATP-binding region ATPase domain protein; PAS fold domain protein. (543 aa)    
Predicted Functional Partners:
AEG60273.1
Response regulator receiver; KEGG: drm:Dred_1864 two component LuxR family transcriptional regulator; PFAM: response regulator receiver; regulatory protein LuxR; SMART: response regulator receiver; regulatory protein LuxR.
 
 
 0.973
AEG59936.1
Sensor DegS domain protein; KEGG: drm:Dred_2107 histidine kinase; PFAM: Sensor DegS domain protein; histidine kinase dimerisation and phosphoacceptor region; ATP-binding region ATPase domain protein; SMART: ATP-binding region ATPase domain protein.
  
  
 
0.927
AEG59935.1
Response regulator receiver; KEGG: drm:Dred_2108 two component LuxR family transcriptional regulator; PFAM: response regulator receiver; regulatory protein LuxR; SMART: response regulator receiver; regulatory protein LuxR.
 
 
 0.869
AEG61405.1
KEGG: dra:DR_0987 DNA-binding response regulator; PFAM: response regulator receiver; regulatory protein LuxR; SMART: response regulator receiver; regulatory protein LuxR.
 
 
 0.858
AEG61202.1
KEGG: sth:STH3096 two-component response regulator; PFAM: response regulator receiver; regulatory protein LuxR; SMART: regulatory protein LuxR; response regulator receiver.
 
 
 0.857
AEG62029.1
Regulatory protein LuxR; KEGG: bbe:BBR47_29850 probable transcriptional regulator; PFAM: regulatory protein LuxR; SMART: regulatory protein LuxR.
 
 
 0.800
AEG60272.1
KEGG: drm:Dred_1865 hypothetical protein.
       0.721
AEG59916.1
TIGRFAM: PAS sensor protein; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold-4 domain protein; PAS fold domain protein; response regulator receiver; Hpt domain protein; KEGG: drm:Dred_2145 multi-sensor hybrid histidine kinase; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS domain containing protein; response regulator receiver.
  
 
 0.641
AEG60856.1
KEGG: drm:Dred_1426 hypothetical protein.
  
     0.523
AEG60218.1
KEGG: drm:Dred_1904 hypothetical protein.
 
     0.521
Your Current Organism:
Desulfotomaculum ruminis
NCBI taxonomy Id: 696281
Other names: D. ruminis DSM 2154, Desulfotomaculum ruminis ATCC 23193, Desulfotomaculum ruminis DL, Desulfotomaculum ruminis DSM 2154, Desulfotomaculum ruminis str. DSM 2154, Desulfotomaculum ruminis strain DSM 2154
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