STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEG60360.1PFAM: metallophosphoesterase; KEGG: drm:Dred_0560 phosphodiesterase. (238 aa)    
Predicted Functional Partners:
AEG58855.1
PFAM: Ankyrin; KEGG: spu:585023 similar to NACHT domain protein, putative.
    
 
 0.742
AEG59209.1
Non-canonical purine NTP pyrophosphatase, rdgB/HAM1 family; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.
  
  
 0.660
AEG60797.1
Peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.
  
 
 0.533
AEG61188.1
CBS domain containing protein; KEGG: drm:Dred_1131 polynucleotide adenylyltransferase region; PFAM: CBS domain containing protein; phosphoesterase RecJ domain protein; phosphoesterase DHHA1; Polynucleotide adenylyltransferase region; SMART: CBS domain containing protein; Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.
  
 
 0.529
AEG60361.1
Regulatory protein ArsR; KEGG: swo:Swol_0936 regulator of arsenical resistance; PFAM: regulatory protein ArsR; SMART: regulatory protein ArsR.
       0.522
AEG60363.1
Arsenite-activated ATPase ArsA; KEGG: swo:Swol_0938 arsenite-transporting ATPase; TIGRFAM: arsenite-activated ATPase ArsA.
   
   0.430
AEG60362.1
PFAM: Arsenical resistance operon trans-acting repressor ArsD; KEGG: swo:Swol_0937 arsenical resistance operon trans-acting repressor.
       0.428
AEG60359.1
KEGG: dsy:DSY3578 hypothetical protein.
       0.424
AEG59970.1
Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family.
       0.406
Your Current Organism:
Desulfotomaculum ruminis
NCBI taxonomy Id: 696281
Other names: D. ruminis DSM 2154, Desulfotomaculum ruminis ATCC 23193, Desulfotomaculum ruminis DL, Desulfotomaculum ruminis DSM 2154, Desulfotomaculum ruminis str. DSM 2154, Desulfotomaculum ruminis strain DSM 2154
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