Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AEG60375.1PFAM: peptidase M24; creatinase; KEGG: aac:Aaci_1001 peptidase M24; Belongs to the peptidase M24B family. (364 aa)    
Predicted Functional Partners:
AEG60374.1
PFAM: extracellular solute-binding protein family 5; KEGG: drm:Dred_1562 extracellular solute-binding protein.
  
  
 0.780
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
   
   0.657
AEG61255.1
KEGG: drm:Dred_1092 peptidase T-like protein; TIGRFAM: peptidase T-like protein; PFAM: peptidase M20; peptidase dimerisation domain protein.
  
 
 0.646
AEG60377.1
KEGG: drm:Dred_1560 5-oxoprolinase (ATP-hydrolyzing); PFAM: Hydantoinase B/oxoprolinase.
       0.634
AEG60371.1
TIGRFAM: oligopeptide/dipeptide ABC transporter, ATPase subunit; PFAM: ABC transporter related; Oligopeptide/dipeptide ABC transporter domain protein; KEGG: drm:Dred_1565 oligopeptide/dipeptide ABC transporter, ATPase subunit; SMART: AAA ATPase; Belongs to the ABC transporter superfamily.
 
  
 0.618
AEG60378.1
KEGG: drm:Dred_1559 5-oxoprolinase (ATP-hydrolyzing); PFAM: Hydantoinase/oxoprolinase; Hydantoinaseoxoprolinase domain protein.
       0.618
AEG60376.1
PFAM: Cupin 2 conserved barrel domain protein; KEGG: drm:Dred_1561 cupin 2 domain-containing protein.
       0.605
AEG60372.1
PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: drm:Dred_1564 binding-protein-dependent transport systems inner membrane component.
  
  
 0.582
valS
valyl-tRNA synthetase; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner; Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
 
   
 0.576
AEG60373.1
PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: drm:Dred_1563 binding-protein-dependent transport systems inner membrane component.
     
 0.571
Your Current Organism:
Desulfotomaculum ruminis
NCBI taxonomy Id: 696281
Other names: D. ruminis DSM 2154, Desulfotomaculum ruminis ATCC 23193, Desulfotomaculum ruminis DL, Desulfotomaculum ruminis DSM 2154, Desulfotomaculum ruminis str. DSM 2154, Desulfotomaculum ruminis strain DSM 2154
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