STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEG60384.1KEGG: dae:Dtox_3366 methyl-accepting chemotaxis sensory transducer; PFAM: chemotaxis sensory transducer; histidine kinase HAMP region domain protein; CHASE3 domain protein; SMART: chemotaxis sensory transducer; histidine kinase HAMP region domain protein. (526 aa)    
Predicted Functional Partners:
AEG59857.1
CheW domain protein; KEGG: aoe:Clos_1960 response regulator receiver modulated CheW protein; PFAM: CheW domain protein; response regulator receiver; SMART: CheW domain protein; response regulator receiver.
 
 0.991
AEG59482.1
CheW domain protein; KEGG: drm:Dred_2440 CheA signal transduction histidine kinase; PFAM: CheW domain protein; ATP-binding region ATPase domain protein; P2 response regulator binding domain protein; Hpt domain protein; Signal transducing histidine kinase homodimeric; SMART: CheW domain protein; Hpt domain protein; ATP-binding region ATPase domain protein.
 
 0.990
AEG59099.1
CheW domain protein; KEGG: dau:Daud_1560 putative CheW protein; PFAM: CheW domain protein; SMART: CheW domain protein.
 
 0.966
AEG59481.1
CheW domain protein; KEGG: drm:Dred_2441 putative CheW protein; PFAM: CheW domain protein; SMART: CheW domain protein.
 
 0.966
AEG59895.1
CheW domain protein; KEGG: drm:Dred_2154 putative CheW protein; PFAM: CheW domain protein; SMART: CheW domain protein.
 
 0.966
AEG58372.1
CheW domain protein; KEGG: dau:Daud_1560 putative CheW protein; PFAM: CheW domain protein; SMART: CheW domain protein.
 
 0.965
cheB
CheB methylesterase; Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid. Belongs to the CheB family.
 
 0.955
AEG59536.1
Protein-glutamate O-methyltransferase; PFAM: MCP methyltransferase CheR-type; KEGG: drm:Dred_2384 protein-glutamate O-methyltransferase; SMART: MCP methyltransferase CheR-type.
 
 0.955
cheD
CheD family protein; Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis; Belongs to the CheD family.
 
  0.935
AEG61336.1
TIGRFAM: PAS sensor protein; PFAM: ATP-binding region ATPase domain protein; PAS fold domain protein; response regulator receiver; GAF domain protein; histidine kinase A domain protein; KEGG: dae:Dtox_0050 PAS/PAC sensor signal transduction histidine kinase; SMART: ATP-binding region ATPase domain protein; response regulator receiver; PAS domain containing protein; PAC repeat-containing protein; GAF domain protein; histidine kinase A domain protein.
 
 
 0.899
Your Current Organism:
Desulfotomaculum ruminis
NCBI taxonomy Id: 696281
Other names: D. ruminis DSM 2154, Desulfotomaculum ruminis ATCC 23193, Desulfotomaculum ruminis DL, Desulfotomaculum ruminis DSM 2154, Desulfotomaculum ruminis str. DSM 2154, Desulfotomaculum ruminis strain DSM 2154
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