STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEG60394.1TIGRFAM: pyruvate formate-lyase; KEGG: aoe:Clos_2688 pyruvate formate-lyase; PFAM: pyruvate formate-lyase PFL; formate C-acetyltransferase glycine radical. (789 aa)    
Predicted Functional Partners:
AEG60393.1
TIGRFAM: glycyl-radical enzyme activating protein family; KEGG: drm:Dred_2966 glycyl-radical activating family protein; PFAM: Radical SAM domain protein.
 
  
 0.969
cutD
Glycyl-radical enzyme activating protein family; Catalyzes activation of the choline trimethylamine-lyase CutC under anaerobic conditions by generation of an organic free radical on a glycine residue, via an homolytic cleavage of S-adenosyl-L-methionine (SAM).
 
  
 0.889
AEG58762.1
TIGRFAM: glycyl-radical enzyme activating protein family; KEGG: drm:Dred_2752 glycyl-radical activating family protein; PFAM: Radical SAM domain protein.
 
  
 0.878
AEG58794.1
TIGRFAM: glycyl-radical enzyme activating protein family; KEGG: cdf:CD3283 putative pyruvate formate-lyase 3 activating enzyme; PFAM: Radical SAM domain protein.
 
  
 0.878
AEG60405.1
Pyruvate formate-lyase activating enzyme; Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine; Belongs to the organic radical-activating enzymes family.
 
  
 0.828
AEG60395.1
GntR domain protein; KEGG: rxy:Rxyl_2260 GntR family transcriptional regulator; PFAM: GntR domain protein; regulatory protein GntR HTH; SMART: regulatory protein GntR HTH.
       0.774
AEG60392.1
PFAM: 3-hydroxyacyl-CoA dehydrogenase NAD-binding; 3-hydroxyacyl-CoA dehydrogenase domain-containing protein; KEGG: dhd:Dhaf_3999 3-hydroxyacyl-CoA dehydrogenase NAD-binding.
     
 0.726
AEG61531.1
Anaerobic ribonucleoside-triphosphate reductase activating protein; Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.
 
  
 0.633
AEG58367.1
KEGG: dae:Dtox_2061 pyruvate dehydrogenase (acetyl-transferring); PFAM: dehydrogenase E1 component.
   
  
 0.528
AEG58643.1
PFAM: Radical SAM domain protein; KEGG: drm:Dred_0270 radical SAM domain-containing protein.
  
  
 0.452
Your Current Organism:
Desulfotomaculum ruminis
NCBI taxonomy Id: 696281
Other names: D. ruminis DSM 2154, Desulfotomaculum ruminis ATCC 23193, Desulfotomaculum ruminis DL, Desulfotomaculum ruminis DSM 2154, Desulfotomaculum ruminis str. DSM 2154, Desulfotomaculum ruminis strain DSM 2154
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