Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AEG60505.1KEGG: toc:Toce_1565 phosphate butyryltransferase; PFAM: phosphate acetyl/butaryl transferase. (314 aa)    
Predicted Functional Partners:
buk
KEGG: amt:Amet_4431 butyrate kinase; TIGRFAM: butyrate kinase; PFAM: acetate and butyrate kinase; Belongs to the acetokinase family.
 
 0.999
ackA
Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family.
 
 0.998
AEG58904.1
PFAM: iron-containing alcohol dehydrogenase; Aldehyde Dehydrogenase; KEGG: drm:Dred_1495 bifunctional acetaldehyde-CoA/alcohol dehydrogenase; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.
  
 
 0.947
AEG60328.1
KEGG: drm:Dred_3266 acetaldehyde dehydrogenase (acetylating); TIGRFAM: acetaldehyde dehydrogenase (acetylating); PFAM: Aldehyde Dehydrogenase.
  
 
 0.915
AEG60344.1
KEGG: drm:Dred_3280 acetaldehyde dehydrogenase (acetylating); TIGRFAM: acetaldehyde dehydrogenase (acetylating); PFAM: Aldehyde Dehydrogenase.
  
 
 0.915
AEG60226.1
PFAM: AMP-dependent synthetase and ligase; KEGG: chy:CHY_0572 acetyl-coenzyme A synthetase family protein.
  
 
 0.911
acsA
acetate/CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.
  
 
 0.823
AEG58367.1
KEGG: dae:Dtox_2061 pyruvate dehydrogenase (acetyl-transferring); PFAM: dehydrogenase E1 component.
  
  
 0.690
AEG59916.1
TIGRFAM: PAS sensor protein; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold-4 domain protein; PAS fold domain protein; response regulator receiver; Hpt domain protein; KEGG: drm:Dred_2145 multi-sensor hybrid histidine kinase; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS domain containing protein; response regulator receiver.
  
  
 0.680
AEG58875.1
KEGG: dhd:Dhaf_4634 sulfoacetaldehyde acetyltransferase; TIGRFAM: sulfoacetaldehyde acetyltransferase; PFAM: thiamine pyrophosphate central domain-containing protein; thiamine pyrophosphate TPP-binding domain-containing protein; Belongs to the TPP enzyme family.
  
 
 0.655
Your Current Organism:
Desulfotomaculum ruminis
NCBI taxonomy Id: 696281
Other names: D. ruminis DSM 2154, Desulfotomaculum ruminis ATCC 23193, Desulfotomaculum ruminis DL, Desulfotomaculum ruminis DSM 2154, Desulfotomaculum ruminis str. DSM 2154, Desulfotomaculum ruminis strain DSM 2154
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