Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AEG60521.12-oxoglutarate synthase; KEGG: hmo:HM1_2763 2-oxoacid:ferredoxin oxidoreductase, beta subunit; PFAM: thiamine pyrophosphate TPP-binding domain-containing protein. (272 aa)    
Predicted Functional Partners:
AEG60522.1
PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; Transketolase domain-containing protein; KEGG: pth:PTH_0847 pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, alpha subunit.
 
 0.999
AEG58400.1
PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; KEGG: drm:Dred_0047 pyruvate flavodoxin/ferredoxin oxidoreductase domain-containing protein.
 
 0.996
AEG61258.1
3-methyl-2-oxobutanoate dehydrogenase (ferredoxin); KEGG: adg:Adeg_1385 2-ketoisovalerate ferredoxin reductase; PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein.
 
 0.995
AEG60520.1
PFAM: Pyruvate/ketoisovalerate oxidoreductase, catalytic domain; KEGG: hmo:HM1_2762 2-oxoglutarate oxidoreductase, gamma subunit, putative.
 
 0.990
AEG59628.1
KEGG: drm:Dred_2312 pyruvate kinase; TIGRFAM: pyruvate kinase; PFAM: Pyruvate kinase barrel; Pyruvate kinase alpha/beta; PEP-utilising protein mobile region; Belongs to the pyruvate kinase family.
   
 0.948
AEG60523.1
KEGG: aco:Amico_0794 4Fe-4S ferredoxin iron-sulfur binding domain protein.
 
 
 0.947
AEG61293.1
KEGG: drm:Dred_1064 pyruvate carboxylase subunit B; TIGRFAM: acetyl-CoA carboxylase, biotin carboxyl carrier protein; PFAM: Conserved carboxylase region; pyruvate carboxyltransferase; biotin/lipoyl attachment domain-containing protein.
  
 
 0.944
AEG61256.1
Pyruvate/ketoisovalerate oxidoreductase, gamma subunit; KEGG: tjr:TherJR_1676 pyruvate/ketoisovalerate oxidoreductase; TIGRFAM: pyruvate/ketoisovalerate oxidoreductase, gamma subunit; PFAM: Pyruvate/ketoisovalerate oxidoreductase, catalytic domain.
 
 0.935
AEG58401.1
PFAM: thiamine pyrophosphate TPP-binding domain-containing protein; KEGG: drm:Dred_0048 thiamine pyrophosphate binding domain-containing protein.
  
  
 
0.918
AEG61257.1
PFAM: thiamine pyrophosphate TPP-binding domain-containing protein; KEGG: hor:Hore_06790 3-methyl-2-oxobutanoate dehydrogenase (ferredoxin), beta subunit.
  
  
 
0.917
Your Current Organism:
Desulfotomaculum ruminis
NCBI taxonomy Id: 696281
Other names: D. ruminis DSM 2154, Desulfotomaculum ruminis ATCC 23193, Desulfotomaculum ruminis DL, Desulfotomaculum ruminis DSM 2154, Desulfotomaculum ruminis str. DSM 2154, Desulfotomaculum ruminis strain DSM 2154
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