STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEG60613.1PFAM: nickel-dependent hydrogenase large subunit; KEGG: dau:Daud_1940 hydrogen:quinone oxidoreductase. (469 aa)    
Predicted Functional Partners:
AEG60614.1
TIGRFAM: hydrogenase (NiFe) small subunit HydA; KEGG: dau:Daud_1939 hydrogenase (NiFe) small subunit HydA; PFAM: NADH ubiquinone oxidoreductase 20 kDa subunit.
 
 0.999
hypA
Hydrogenase expression/synthesis HypA; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.
 
 
 0.987
AEG61578.1
PFAM: methyl-viologen-reducing hydrogenase delta subunit; fumarate reductase/succinate dehydrogenase flavoprotein domain protein; KEGG: drm:Dred_0639 methyl-viologen-reducing hydrogenase, delta subunit.
  
 
 0.976
AEG60611.1
Manually curated; TIGRFAM: hydrogenase maturation protease; KEGG: slp:Slip_0388 hydrogenase maturation protease; PFAM: peptidase M52 hydrogen uptake protein.
 
  
 0.967
AEG60608.1
KEGG: tye:THEYE_A1019 hydrogenase expression/formation protein HypD; TIGRFAM: hydrogenase expression/formation protein HypD; PFAM: hydrogenase formation HypD protein.
 
 
 0.960
AEG60607.1
Manually curated; TIGRFAM: hydrogenase expression/formation protein HypE; KEGG: tjr:TherJR_1303 hydrogenase expression/formation protein HypE; PFAM: AIR synthase related protein domain protein; AIR synthase related protein.
 
   
 0.956
AEG60921.1
KEGG: drm:Dred_1330 formate dehydrogenase; PFAM: coenzyme F420 hydrogenase/dehydrogenase beta subunit domain protein.
  
 
 0.954
AEG60610.1
KEGG: tjr:TherJR_1300 (NiFe) hydrogenase maturation protein HypF; TIGRFAM: [NiFe] hydrogenase maturation protein HypF; PFAM: SUA5/yciO/yrdC domain; acylphosphatase.
 
 
 
 0.951
AEG60609.1
KEGG: dal:Dalk_2013 hydrogenase assembly chaperone HypC/HupF; TIGRFAM: hydrogenase assembly chaperone hypC/hupF; PFAM: hydrogenase expression/formation protein (HUPF/HYPC).
 
 
 0.946
AEG60605.1
KEGG: dol:Dole_0298 hydrogenase accessory protein HypB; TIGRFAM: hydrogenase accessory protein HypB; PFAM: cobalamin synthesis protein P47K.
 
  
 0.940
Your Current Organism:
Desulfotomaculum ruminis
NCBI taxonomy Id: 696281
Other names: D. ruminis DSM 2154, Desulfotomaculum ruminis ATCC 23193, Desulfotomaculum ruminis DL, Desulfotomaculum ruminis DSM 2154, Desulfotomaculum ruminis str. DSM 2154, Desulfotomaculum ruminis strain DSM 2154
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