STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEG60732.1Sporulation protein YtaF; Probably functions as a manganese efflux pump. (212 aa)    
Predicted Functional Partners:
coaE
dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family.
  
    0.854
mutM
formamidopyrimidine-DNA glycosylase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
  
    0.726
AEG58847.1
KEGG: drm:Dred_2960 hypothetical protein.
  
     0.691
AEG61226.1
PFAM: GerA spore germination protein; KEGG: drm:Dred_1110 GerA spore germination protein.
  
     0.654
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
  
    0.625
AEG60734.1
PFAM: Lytic transglycosylase catalytic; KEGG: drm:Dred_1595 lytic transglycosylase, catalytic.
       0.624
AEG60174.1
KEGG: drm:Dred_1943 dipicolinate synthase subunit A; TIGRFAM: dipicolinic acid synthetase, A subunit; PFAM: D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding.
  
     0.588
AEG61819.1
KEGG: drm:Dred_3068 hypothetical protein.
  
     0.586
AEG58489.1
KEGG: drm:Dred_0118 YabP family protein; TIGRFAM: sporulation protein YabP; PFAM: YabP family protein.
  
   
 0.556
AEG61295.1
KEGG: drm:Dred_1062 hypothetical protein.
  
    0.552
Your Current Organism:
Desulfotomaculum ruminis
NCBI taxonomy Id: 696281
Other names: D. ruminis DSM 2154, Desulfotomaculum ruminis ATCC 23193, Desulfotomaculum ruminis DL, Desulfotomaculum ruminis DSM 2154, Desulfotomaculum ruminis str. DSM 2154, Desulfotomaculum ruminis strain DSM 2154
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