STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEG60741.1KEGG: drm:Dred_1584 stage II sporulation E family protein; PFAM: Stage II sporulation protein E; SMART: protein phosphatase 2C domain protein. (383 aa)    
Predicted Functional Partners:
AEG59916.1
TIGRFAM: PAS sensor protein; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold-4 domain protein; PAS fold domain protein; response regulator receiver; Hpt domain protein; KEGG: drm:Dred_2145 multi-sensor hybrid histidine kinase; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS domain containing protein; response regulator receiver.
  
  
 0.988
spoIIAB
Anti-sigma F factor; Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti- anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition.
  
 
 0.953
AEG60740.1
PAS fold domain protein; KEGG: drm:Dred_1585 putative PAS/PAC sensor protein; PFAM: PAS fold domain protein; Fe-S cluster domain protein; SMART: PAS domain containing protein.
 
   
 0.934
AEG61336.1
TIGRFAM: PAS sensor protein; PFAM: ATP-binding region ATPase domain protein; PAS fold domain protein; response regulator receiver; GAF domain protein; histidine kinase A domain protein; KEGG: dae:Dtox_0050 PAS/PAC sensor signal transduction histidine kinase; SMART: ATP-binding region ATPase domain protein; response regulator receiver; PAS domain containing protein; PAC repeat-containing protein; GAF domain protein; histidine kinase A domain protein.
  
  
 0.780
AEG59643.1
PFAM: Fe-S cluster domain protein; KEGG: drm:Dred_2305 ferredoxin 2.
 
     0.771
AEG59513.1
KEGG: drm:Dred_2407 flagellar motor switch protein FliG; TIGRFAM: flagellar motor switch protein FliG; PFAM: flagellar motor switch protein FliG.
  
    0.744
AEG62014.1
TIGRFAM: diguanylate cyclase; PAS sensor protein; PFAM: EAL domain protein; GGDEF domain containing protein; histidine kinase HAMP region domain protein; PAS fold-4 domain protein; KEGG: dae:Dtox_0767 diguanylate cyclase/phosphodiesterase with PAS/PAC and GAF sensor(s); SMART: EAL domain protein; GGDEF domain containing protein; histidine kinase HAMP region domain protein; PAS domain containing protein.
  
  
 0.743
AEG59509.1
Flagellar basal-body rod protein FlgB; Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.
   
    0.724
AEG59043.1
TIGRFAM: diguanylate cyclase; PFAM: EAL domain protein; CBS domain containing protein; GGDEF domain containing protein; KEGG: dae:Dtox_1949 diguanylate cyclase/phosphodiesterase; SMART: EAL domain protein; GGDEF domain containing protein.
  
  
 0.701
AEG59900.1
PFAM: biotin and thiamin synthesis associated; Radical SAM domain protein; KEGG: drm:Dred_2150 thiamine biosynthesis protein ThiH.
  
  
 0.688
Your Current Organism:
Desulfotomaculum ruminis
NCBI taxonomy Id: 696281
Other names: D. ruminis DSM 2154, Desulfotomaculum ruminis ATCC 23193, Desulfotomaculum ruminis DL, Desulfotomaculum ruminis DSM 2154, Desulfotomaculum ruminis str. DSM 2154, Desulfotomaculum ruminis strain DSM 2154
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