STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
addBATP-dependent nuclease subunit B; ATP-dependent DNA helicase; Belongs to the helicase family. AddB/RexB type 1 subfamily. (1157 aa)    
Predicted Functional Partners:
addA
Recombination helicase AddA; ATP-dependent DNA helicase.
 
 
 0.999
AEG59456.1
PFAM: protein of unknown function DUF633; KEGG: drm:Dred_2460 hypothetical protein.
 
     0.535
AEG59457.1
PFAM: protein of unknown function DUF34; KEGG: drm:Dred_2459 hypothetical protein; Belongs to the GTP cyclohydrolase I type 2/NIF3 family.
 
     0.516
dinG
DNA polymerase III, epsilon subunit; 3'-5' exonuclease.
     
 0.481
pheT
KEGG: drm:Dred_1620 phenylalanyl-tRNA synthetase subunit beta; TIGRFAM: phenylalanyl-tRNA synthetase, beta subunit.
  
    0.467
AEG61478.1
KEGG: drm:Dred_0731 single-stranded-DNA-specific exonuclease RecJ; TIGRFAM: single-stranded-DNA-specific exonuclease RecJ; PFAM: phosphoesterase RecJ domain protein; phosphoesterase DHHA1.
     
 0.466
AEG60865.1
PFAM: Penicillinase repressor; KEGG: cbe:Cbei_3104 CopY family transcriptional regulator.
       0.454
AEG60866.1
KEGG: cth:Cthe_1810 peptidase M56, BlaR1; PFAM: peptidase M56 BlaR1; cell wall hydrolase/autolysin; SMART: cell wall hydrolase/autolysin.
       0.443
AEG59258.1
PFAM: metallophosphoesterase; KEGG: drm:Dred_2571 metallophosphoesterase.
  
  
 0.419
mutL
DNA mismatch repair protein MutL; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.
   
  
 0.415
Your Current Organism:
Desulfotomaculum ruminis
NCBI taxonomy Id: 696281
Other names: D. ruminis DSM 2154, Desulfotomaculum ruminis ATCC 23193, Desulfotomaculum ruminis DL, Desulfotomaculum ruminis DSM 2154, Desulfotomaculum ruminis str. DSM 2154, Desulfotomaculum ruminis strain DSM 2154
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.