STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEG61212.1KEGG: drm:Dred_0537 CRISPR-associated Csh2 family protein; TIGRFAM: CRISPR-associated protein, Csh2 family; CRISPR-associated protein, CT1132 family; PFAM: CRISPR-associated protein TM1801. (325 aa)    
Predicted Functional Partners:
AEG61211.1
TIGRFAM: CRISPR-associated protein Cas5; KEGG: drm:Dred_0538 CRISPR-associated Cas5 family Hmari subtype protein.
 
  
 0.960
AEG61210.1
TIGRFAM: CRISPR-associated HD domain protein; CRISPR-associated helicase Cas3; PFAM: DEAD/DEAH box helicase domain protein; helicase domain protein; KEGG: drm:Dred_0539 CRISPR-associated helicase Cas3; SMART: DEAD-like helicase; helicase domain protein.
 
  
 0.955
AEG59676.1
KEGG: mla:Mlab_0849 hypothetical protein; TIGRFAM: CRISPR-associated protein Cas5 family; CRISPR-associated protein Cas5; PFAM: CRISPR-associated protein, Cas5.
 
 
 
 0.942
AEG59677.1
KEGG: dae:Dtox_3649 CRISPR-associated protein, Csd1 family; TIGRFAM: CRISPR-associated protein, Csd1 family; PFAM: CRISPR-associated protein CT1133.
 
 
 
 0.920
AEG61214.1
CRISPR-associated protein Cas6; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).
 
   
 0.918
AEG61213.1
PFAM: CRISPR-associated protein TM1802; KEGG: drm:Dred_0536 hypothetical protein.
 
    0.913
cas1-2
CRISPR-associated protein Cas1; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
 
   
 0.872
AEG61209.1
CRISPR-associated protein Cas4; CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Belongs to the CRISPR-associated exonuclease Cas4 family.
 
   
 0.848
cas2-2
CRISPR-associated protein Cas2; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
 
   
 0.842
AEG59675.1
TIGRFAM: CRISPR-associated HD domain protein; CRISPR-associated helicase Cas3; PFAM: helicase domain protein; KEGG: amt:Amet_1662 CRISPR-associated helicase Cas3; SMART: DEAD-like helicase.
 
  
 0.803
Your Current Organism:
Desulfotomaculum ruminis
NCBI taxonomy Id: 696281
Other names: D. ruminis DSM 2154, Desulfotomaculum ruminis ATCC 23193, Desulfotomaculum ruminis DL, Desulfotomaculum ruminis DSM 2154, Desulfotomaculum ruminis str. DSM 2154, Desulfotomaculum ruminis strain DSM 2154
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.