Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AEG61213.1PFAM: CRISPR-associated protein TM1802; KEGG: drm:Dred_0536 hypothetical protein. (673 aa)    
Predicted Functional Partners:
AEG61211.1
TIGRFAM: CRISPR-associated protein Cas5; KEGG: drm:Dred_0538 CRISPR-associated Cas5 family Hmari subtype protein.
 
    0.951
AEG61212.1
KEGG: drm:Dred_0537 CRISPR-associated Csh2 family protein; TIGRFAM: CRISPR-associated protein, Csh2 family; CRISPR-associated protein, CT1132 family; PFAM: CRISPR-associated protein TM1801.
 
    0.915
AEG61210.1
TIGRFAM: CRISPR-associated HD domain protein; CRISPR-associated helicase Cas3; PFAM: DEAD/DEAH box helicase domain protein; helicase domain protein; KEGG: drm:Dred_0539 CRISPR-associated helicase Cas3; SMART: DEAD-like helicase; helicase domain protein.
 
     0.878
AEG61214.1
CRISPR-associated protein Cas6; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).
       0.775
AEG60058.1
PFAM: AAA-4 family protein; KEGG: drm:Dred_2059 putative transcriptional regulator.
  
     0.774
AEG61121.1
PFAM: Ion transport 2 domain protein; KEGG: drm:Dred_1173 ion transport 2 domain-containing protein.
  
     0.774
AEG60940.1
PFAM: hypothetical protein; KEGG: drm:Dred_1314 hypothetical protein.
  
     0.773
AEG59259.1
PFAM: SMC domain protein; KEGG: drm:Dred_2570 SMC domain-containing protein.
  
     0.772
AEG59140.1
KEGG: drm:Dred_2743 hypothetical protein.
  
     0.769
AEG60218.1
KEGG: drm:Dred_1904 hypothetical protein.
  
     0.764
Your Current Organism:
Desulfotomaculum ruminis
NCBI taxonomy Id: 696281
Other names: D. ruminis DSM 2154, Desulfotomaculum ruminis ATCC 23193, Desulfotomaculum ruminis DL, Desulfotomaculum ruminis DSM 2154, Desulfotomaculum ruminis str. DSM 2154, Desulfotomaculum ruminis strain DSM 2154
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