STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEG61257.1PFAM: thiamine pyrophosphate TPP-binding domain-containing protein; KEGG: hor:Hore_06790 3-methyl-2-oxobutanoate dehydrogenase (ferredoxin), beta subunit. (249 aa)    
Predicted Functional Partners:
AEG61258.1
3-methyl-2-oxobutanoate dehydrogenase (ferredoxin); KEGG: adg:Adeg_1385 2-ketoisovalerate ferredoxin reductase; PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein.
 
 0.999
AEG61256.1
Pyruvate/ketoisovalerate oxidoreductase, gamma subunit; KEGG: tjr:TherJR_1676 pyruvate/ketoisovalerate oxidoreductase; TIGRFAM: pyruvate/ketoisovalerate oxidoreductase, gamma subunit; PFAM: Pyruvate/ketoisovalerate oxidoreductase, catalytic domain.
 
 0.998
AEG58400.1
PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; KEGG: drm:Dred_0047 pyruvate flavodoxin/ferredoxin oxidoreductase domain-containing protein.
 
 0.997
AEG60522.1
PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; Transketolase domain-containing protein; KEGG: pth:PTH_0847 pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, alpha subunit.
 
 0.996
AEG61259.1
Ferredoxin; KEGG: pth:PTH_1204 ferredoxin.
 
 
 0.978
AEG61293.1
KEGG: drm:Dred_1064 pyruvate carboxylase subunit B; TIGRFAM: acetyl-CoA carboxylase, biotin carboxyl carrier protein; PFAM: Conserved carboxylase region; pyruvate carboxyltransferase; biotin/lipoyl attachment domain-containing protein.
  
 
 0.939
AEG58402.1
Pyruvate/ketoisovalerate oxidoreductase, gamma subunit; KEGG: drm:Dred_0049 pyruvate ferredoxin/flavodoxin oxidoreductase; TIGRFAM: pyruvate/ketoisovalerate oxidoreductase, gamma subunit; PFAM: Pyruvate/ketoisovalerate oxidoreductase, catalytic domain.
 
 
 0.934
AEG59628.1
KEGG: drm:Dred_2312 pyruvate kinase; TIGRFAM: pyruvate kinase; PFAM: Pyruvate kinase barrel; Pyruvate kinase alpha/beta; PEP-utilising protein mobile region; Belongs to the pyruvate kinase family.
   
 0.927
AEG59707.1
PFAM: AMP-dependent synthetase and ligase; KEGG: tjr:TherJR_1681 AMP-dependent synthetase and ligase.
 
 
 0.926
AEG58904.1
PFAM: iron-containing alcohol dehydrogenase; Aldehyde Dehydrogenase; KEGG: drm:Dred_1495 bifunctional acetaldehyde-CoA/alcohol dehydrogenase; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.
  
 
 0.919
Your Current Organism:
Desulfotomaculum ruminis
NCBI taxonomy Id: 696281
Other names: D. ruminis DSM 2154, Desulfotomaculum ruminis ATCC 23193, Desulfotomaculum ruminis DL, Desulfotomaculum ruminis DSM 2154, Desulfotomaculum ruminis str. DSM 2154, Desulfotomaculum ruminis strain DSM 2154
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.