STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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Textmining
[Homology]
Score
AEG61293.1KEGG: drm:Dred_1064 pyruvate carboxylase subunit B; TIGRFAM: acetyl-CoA carboxylase, biotin carboxyl carrier protein; PFAM: Conserved carboxylase region; pyruvate carboxyltransferase; biotin/lipoyl attachment domain-containing protein. (632 aa)    
Predicted Functional Partners:
AEG61292.1
acetyl-CoA carboxylase, biotin carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.
 
 
 0.998
accA
acetyl-CoA carboxylase, carboxyl transferase, alpha subunit; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
 
 0.988
accD
acetyl-CoA carboxylase, carboxyl transferase, beta subunit; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family.
 
 0.981
AEG60260.1
PFAM: phosphoenolpyruvate carboxykinase (ATP); KEGG: hmo:HM1_2773 phosphoenolpyruvate carboxykinase; Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.
  
 
 0.966
AEG59628.1
KEGG: drm:Dred_2312 pyruvate kinase; TIGRFAM: pyruvate kinase; PFAM: Pyruvate kinase barrel; Pyruvate kinase alpha/beta; PEP-utilising protein mobile region; Belongs to the pyruvate kinase family.
  
 
 0.964
mdh
Malate dehydrogenase, NAD-dependent; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family.
    
 0.958
AEG58401.1
PFAM: thiamine pyrophosphate TPP-binding domain-containing protein; KEGG: drm:Dred_0048 thiamine pyrophosphate binding domain-containing protein.
  
 
 0.944
AEG58880.1
PFAM: malic protein NAD-binding; malic protein domain protein; amino acid-binding ACT domain protein; KEGG: drm:Dred_2955 malate dehydrogenase.
    
 0.944
AEG60521.1
2-oxoglutarate synthase; KEGG: hmo:HM1_2763 2-oxoacid:ferredoxin oxidoreductase, beta subunit; PFAM: thiamine pyrophosphate TPP-binding domain-containing protein.
  
 
 0.944
AEG61257.1
PFAM: thiamine pyrophosphate TPP-binding domain-containing protein; KEGG: hor:Hore_06790 3-methyl-2-oxobutanoate dehydrogenase (ferredoxin), beta subunit.
  
 
 0.944
Your Current Organism:
Desulfotomaculum ruminis
NCBI taxonomy Id: 696281
Other names: D. ruminis DSM 2154, Desulfotomaculum ruminis ATCC 23193, Desulfotomaculum ruminis DL, Desulfotomaculum ruminis DSM 2154, Desulfotomaculum ruminis str. DSM 2154, Desulfotomaculum ruminis strain DSM 2154
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