STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEG61340.16-phospho-3-hexuloisomerase; KEGG: rru:Rru_A1367 hexulose-6-phosphate isomerase; PFAM: sugar isomerase (SIS). (185 aa)    
Predicted Functional Partners:
pgi
PFAM: phosphoglucose isomerase (PGI); KEGG: drm:Dred_2902 glucose-6-phosphate isomerase; Belongs to the GPI family.
    
 0.921
pfkA
6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
    
 0.914
pfkA-2
Phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily.
    
 0.914
pfp
Phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP- PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions.
    
 0.913
AEG60892.1
TIGRFAM: fructose-1,6-bisphosphatase, class II; KEGG: drm:Dred_1352 fructose 1,6-bisphosphatase II; PFAM: GlpX family protein.
     
 0.903
AEG61827.1
PFAM: Transketolase central region; Transketolase domain-containing protein; KEGG: drm:Dred_3074 transketolase, central region.
     
  0.900
AEG61828.1
PFAM: Transketolase domain-containing protein; KEGG: drm:Dred_3075 transketolase domain-containing protein.
     
  0.900
AEG61341.1
PFAM: Xylose isomerase domain-containing protein TIM barrel; KEGG: msv:Mesil_3059 xylose isomerase domain protein TIM barrel.
 
    0.877
AEG61342.1
PFAM: PfkB domain protein; KEGG: ppp:PHYPADRAFT_121587 hypothetical protein; Belongs to the carbohydrate kinase PfkB family.
 
    0.784
AEG61345.1
PFAM: Alcohol dehydrogenase GroES domain protein; Alcohol dehydrogenase zinc-binding domain protein; KEGG: bss:BSUW23_03100 glucitol (sorbitol) dehydrogenase.
 
    0.582
Your Current Organism:
Desulfotomaculum ruminis
NCBI taxonomy Id: 696281
Other names: D. ruminis DSM 2154, Desulfotomaculum ruminis ATCC 23193, Desulfotomaculum ruminis DL, Desulfotomaculum ruminis DSM 2154, Desulfotomaculum ruminis str. DSM 2154, Desulfotomaculum ruminis strain DSM 2154
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