STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEG61461.1KEGG: toc:Toce_0259 HhH-GPD family protein; PFAM: HhH-GPD family protein; SMART: HhH-GPD family protein. (210 aa)    
Predicted Functional Partners:
AEG61462.1
methylated-DNA/protein-cysteine methyltransferase; Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
 
  
 0.958
AEG61109.1
KEGG: drm:Dred_1180 exodeoxyribonuclease III; TIGRFAM: exodeoxyribonuclease III; exodeoxyribonuclease III Xth; PFAM: Endonuclease/exonuclease/phosphatase.
  
 0.955
AEG61463.1
KEGG: bcu:BCAH820_3221 transcriptional regulator, AraC family; PFAM: Ada metal-binding domain-containing protein; helix-turn-helix- domain containing protein AraC type; SMART: Helix-turn-helix, AraC domain.
 
   
 0.730
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
   
 
 0.674
dinB
DNA-directed DNA polymerase; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.
  
 
 0.575
AEG61614.1
KEGG: drm:Dred_0485 xylose isomerase domain-containing protein; PFAM: Xylose isomerase domain-containing protein TIM barrel; SMART: AP endonuclease family 2.
   
 
 0.523
AEG61460.1
PFAM: copper amine oxidase-like domain-containing protein; KEGG: drm:Dred_1644 copper amine oxidase domain-containing protein.
       0.481
AEG59275.1
PFAM: UvrD/REP helicase; KEGG: mta:Moth_0254 UvrD/REP helicase.
   
 
 0.452
Your Current Organism:
Desulfotomaculum ruminis
NCBI taxonomy Id: 696281
Other names: D. ruminis DSM 2154, Desulfotomaculum ruminis ATCC 23193, Desulfotomaculum ruminis DL, Desulfotomaculum ruminis DSM 2154, Desulfotomaculum ruminis str. DSM 2154, Desulfotomaculum ruminis strain DSM 2154
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