STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
sepF-2Protein of unknown function DUF552; Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA. (144 aa)    
Predicted Functional Partners:
AEG61513.1
Alanine racemase domain protein; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
  
  
 0.957
AEG61511.1
PFAM: protein of unknown function YGGT; KEGG: drm:Dred_0714 protein of unknown function YGGT.
  
  
 0.946
ftsZ
Cell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
  
 
 0.939
AEG61510.1
KEGG: drm:Dred_0715 RNA-binding S4 domain-containing protein.
 
  
 0.915
AEG61509.1
KEGG: drm:Dred_0716 DivIVA family protein; TIGRFAM: DivIVA domain; PFAM: DivIVA family protein.
  
  
 0.891
AEG61514.1
KEGG: drm:Dred_0711 hypothetical protein.
       0.833
AEG61368.1
PFAM: protein of unknown function DUF965; KEGG: drm:Dred_0773 hypothetical protein; Belongs to the UPF0297 family.
  
  
 0.708
AEG61544.1
PFAM: cell division protein FtsA; KEGG: drm:Dred_0683 cell division protein FtsA.
  
 
 0.615
AEG60243.1
PFAM: Aluminium resistance family protein; KEGG: drm:Dred_1879 aluminium resistance family protein.
 
     0.607
AEG60876.1
KEGG: drm:Dred_1368 HSP70 family ATPase.
  
 
 0.595
Your Current Organism:
Desulfotomaculum ruminis
NCBI taxonomy Id: 696281
Other names: D. ruminis DSM 2154, Desulfotomaculum ruminis ATCC 23193, Desulfotomaculum ruminis DL, Desulfotomaculum ruminis DSM 2154, Desulfotomaculum ruminis str. DSM 2154, Desulfotomaculum ruminis strain DSM 2154
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.