STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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Textmining
[Homology]
Score
AEG61540.1Peptidase U4 sporulation factor SpoIIGA; Probable aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE/spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR. Belongs to the peptidase U4 family. (300 aa)    
Predicted Functional Partners:
AEG58495.1
SMART: protein phosphatase 2C domain protein; TIGRFAM: stage II sporulation protein E; KEGG: drm:Dred_0124 phosphoprotein phosphatase; PFAM: Stage II sporulation protein E.
  
  
 0.960
AEG61539.1
RNA polymerase sigma-E factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
 
  
 0.938
AEG61538.1
RNA polymerase sigma-G factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
 
  
 0.926
AEG61640.1
Stage II sporulation protein R; KEGG: drm:Dred_0458 pro-sigma-E processing factor spoIIR; TIGRFAM: stage II sporulation protein R; PFAM: Sporulation stage II protein R.
 
   
 0.918
AEG61537.1
Sporulation protein, YlmC/YmxH family; KEGG: drm:Dred_0688 PRC-barrel domain-containing protein; TIGRFAM: sporulation protein, YlmC/YmxH family; PFAM: PRC-barrel domain protein.
 
     0.873
spoIIAB
Anti-sigma F factor; Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti- anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition.
  
  
 0.870
AEG61301.1
KEGG: drm:Dred_1056 hypothetical protein; TIGRFAM: stage III sporulation protein AA; SMART: AAA ATPase.
  
  
 0.869
AEG61883.1
TIGRFAM: sporulation transcriptional regulator SpoIIID; KEGG: drm:Dred_3145 regulatory protein, DeoR.
  
  
 0.861
AEG61294.1
KEGG: drm:Dred_1063 hypothetical protein.
  
  
 0.802
AEG59423.1
Sporulation protein YqfD; KEGG: drm:Dred_2485 putative stage IV sporulation YqfD; TIGRFAM: sporulation protein YqfD; PFAM: stage IV sporulation YqfD.
  
   
 0.800
Your Current Organism:
Desulfotomaculum ruminis
NCBI taxonomy Id: 696281
Other names: D. ruminis DSM 2154, Desulfotomaculum ruminis ATCC 23193, Desulfotomaculum ruminis DL, Desulfotomaculum ruminis DSM 2154, Desulfotomaculum ruminis str. DSM 2154, Desulfotomaculum ruminis strain DSM 2154
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