STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEG61575.1PFAM: Protein of unknown function DUF2088; KEGG: dae:Dtox_0989 hypothetical protein. (415 aa)    
Predicted Functional Partners:
AEG59752.1
PFAM: 1-(5-phosphoribosyl)-5-amino-4-imidazole-carboxylate (AIR) carboxylase; KEGG: cbe:Cbei_0561 NCAIR mutase (PurE)-related protein.
 
  
 0.929
AEG58522.1
PFAM: asparagine synthase; KEGG: drm:Dred_0151 PP-loop domain-containing protein.
 
  
 0.919
AEG61474.1
KEGG: drm:Dred_0735 beta-lactamase domain-containing protein.
     
  0.900
larC
Protein of unknown function DUF111; Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2+), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor-dependent enzymes. Belongs to the LarC family.
 
  
 0.835
AEG59271.1
KEGG: drm:Dred_2565 cobalt ABC transporter, inner membrane subunit CbiQ; TIGRFAM: cobalt ABC transporter, inner membrane subunit CbiQ; PFAM: cobalt transport protein.
  
  
 0.656
tpiA
Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family.
     
 0.481
AEG58779.1
L-lactate permease family protein, putative; Transports L-lactate across the membrane. Can also transport D-lactate and glycolate; Belongs to the lactate permease family.
     
 0.436
AEG59832.1
L-lactate transport; Transports L-lactate across the membrane. Can also transport D-lactate and glycolate; Belongs to the lactate permease family.
     
 0.436
AEG59833.1
L-lactate transport; Transports L-lactate across the membrane. Can also transport D-lactate and glycolate; Belongs to the lactate permease family.
     
 0.436
AEG59269.1
PFAM: cobalamin (vitamin B12) biosynthesis CbiM protein; KEGG: drm:Dred_2567 cobalamin (vitamin B12) biosynthesis CbiM protein.
  
    0.427
Your Current Organism:
Desulfotomaculum ruminis
NCBI taxonomy Id: 696281
Other names: D. ruminis DSM 2154, Desulfotomaculum ruminis ATCC 23193, Desulfotomaculum ruminis DL, Desulfotomaculum ruminis DSM 2154, Desulfotomaculum ruminis str. DSM 2154, Desulfotomaculum ruminis strain DSM 2154
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