STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEG61637.1PFAM: histidine kinase HAMP region domain protein; KEGG: tjr:TherJR_1822 putative sensor with HAMP domain protein. (382 aa)    
Predicted Functional Partners:
AEG59482.1
CheW domain protein; KEGG: drm:Dred_2440 CheA signal transduction histidine kinase; PFAM: CheW domain protein; ATP-binding region ATPase domain protein; P2 response regulator binding domain protein; Hpt domain protein; Signal transducing histidine kinase homodimeric; SMART: CheW domain protein; Hpt domain protein; ATP-binding region ATPase domain protein.
  
  
  0.831
AEG59538.1
KEGG: drm:Dred_2382 response regulator receiver protein; PFAM: response regulator receiver; SMART: response regulator receiver.
  
  
 0.718
cheB
CheB methylesterase; Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid. Belongs to the CheB family.
 
  
  0.717
AEG59536.1
Protein-glutamate O-methyltransferase; PFAM: MCP methyltransferase CheR-type; KEGG: drm:Dred_2384 protein-glutamate O-methyltransferase; SMART: MCP methyltransferase CheR-type.
 
  
  0.717
AEG59481.1
CheW domain protein; KEGG: drm:Dred_2441 putative CheW protein; PFAM: CheW domain protein; SMART: CheW domain protein.
  
  
  0.712
AEG59857.1
CheW domain protein; KEGG: aoe:Clos_1960 response regulator receiver modulated CheW protein; PFAM: CheW domain protein; response regulator receiver; SMART: CheW domain protein; response regulator receiver.
    
 0.711
cheD
CheD family protein; Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis; Belongs to the CheD family.
  
  
  0.707
AEG59895.1
CheW domain protein; KEGG: drm:Dred_2154 putative CheW protein; PFAM: CheW domain protein; SMART: CheW domain protein.
  
  
  0.705
AEG58372.1
CheW domain protein; KEGG: dau:Daud_1560 putative CheW protein; PFAM: CheW domain protein; SMART: CheW domain protein.
  
  
  0.703
AEG59099.1
CheW domain protein; KEGG: dau:Daud_1560 putative CheW protein; PFAM: CheW domain protein; SMART: CheW domain protein.
  
  
  0.690
Your Current Organism:
Desulfotomaculum ruminis
NCBI taxonomy Id: 696281
Other names: D. ruminis DSM 2154, Desulfotomaculum ruminis ATCC 23193, Desulfotomaculum ruminis DL, Desulfotomaculum ruminis DSM 2154, Desulfotomaculum ruminis str. DSM 2154, Desulfotomaculum ruminis strain DSM 2154
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