STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEG61661.1TIGRFAM: diguanylate cyclase; PAS sensor protein; PFAM: GGDEF domain containing protein; PAS fold domain protein; PAS fold-3 domain protein; metal-dependent phosphohydrolase HD sub domain; KEGG: drm:Dred_1552 diguanylate cyclase with PAS/PAC sensor; SMART: GGDEF domain containing protein; PAS domain containing protein; PAC repeat-containing protein; metal-dependent phosphohydrolase HD region. (602 aa)    
Predicted Functional Partners:
AEG59916.1
TIGRFAM: PAS sensor protein; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold-4 domain protein; PAS fold domain protein; response regulator receiver; Hpt domain protein; KEGG: drm:Dred_2145 multi-sensor hybrid histidine kinase; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS domain containing protein; response regulator receiver.
 
 
 0.995
AEG61336.1
TIGRFAM: PAS sensor protein; PFAM: ATP-binding region ATPase domain protein; PAS fold domain protein; response regulator receiver; GAF domain protein; histidine kinase A domain protein; KEGG: dae:Dtox_0050 PAS/PAC sensor signal transduction histidine kinase; SMART: ATP-binding region ATPase domain protein; response regulator receiver; PAS domain containing protein; PAC repeat-containing protein; GAF domain protein; histidine kinase A domain protein.
 
 
 0.972
AEG60897.1
TIGRFAM: diguanylate cyclase; PAS sensor protein; PFAM: EAL domain protein; GGDEF domain containing protein; GAF domain protein; histidine kinase HAMP region domain protein; PAS fold-4 domain protein; KEGG: drm:Dred_1346 diguanylate cyclase/phosphodiesterase with PAS/PAC and GAF sensor(s); SMART: EAL domain protein; GGDEF domain containing protein; GAF domain protein; histidine kinase HAMP region domain protein; PAS domain containing protein.
 
 
0.967
AEG59101.1
TIGRFAM: diguanylate cyclase; PAS sensor protein; PFAM: EAL domain protein; GGDEF domain containing protein; PAS fold-3 domain protein; PAS fold domain protein; PAS fold-4 domain protein; KEGG: pin:Ping_0949 diguanylate cyclase/phosphodiesterase with PAS/PAC and GAF sensor(s); SMART: EAL domain protein; GGDEF domain containing protein; PAS domain containing protein; PAC repeat-containing protein.
 
 
0.945
AEG59857.1
CheW domain protein; KEGG: aoe:Clos_1960 response regulator receiver modulated CheW protein; PFAM: CheW domain protein; response regulator receiver; SMART: CheW domain protein; response regulator receiver.
  
 
 0.944
AEG59043.1
TIGRFAM: diguanylate cyclase; PFAM: EAL domain protein; CBS domain containing protein; GGDEF domain containing protein; KEGG: dae:Dtox_1949 diguanylate cyclase/phosphodiesterase; SMART: EAL domain protein; GGDEF domain containing protein.
 
 
 0.939
AEG62014.1
TIGRFAM: diguanylate cyclase; PAS sensor protein; PFAM: EAL domain protein; GGDEF domain containing protein; histidine kinase HAMP region domain protein; PAS fold-4 domain protein; KEGG: dae:Dtox_0767 diguanylate cyclase/phosphodiesterase with PAS/PAC and GAF sensor(s); SMART: EAL domain protein; GGDEF domain containing protein; histidine kinase HAMP region domain protein; PAS domain containing protein.
 
 
0.931
AEG60980.1
ATP-binding region ATPase domain protein; KEGG: bss:BSUW23_17900 two-component sensor histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; Diverse 7TM receptor transmembrane region; glycoside hydrolase family 2 sugar binding; response regulator receiver; histidine kinase internal region; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; response regulator receiver.
 
 
 0.915
AEG58317.1
KEGG: drm:Dred_0009 metal dependent phosphohydrolase; PFAM: metal-dependent phosphohydrolase HD sub domain; SMART: metal-dependent phosphohydrolase HD region.
 
 
0.850
AEG58967.1
EAL domain protein; KEGG: drm:Dred_0836 diguanylate phosphodiesterase; PFAM: EAL domain protein; SMART: EAL domain protein.
 
 0.849
Your Current Organism:
Desulfotomaculum ruminis
NCBI taxonomy Id: 696281
Other names: D. ruminis DSM 2154, Desulfotomaculum ruminis ATCC 23193, Desulfotomaculum ruminis DL, Desulfotomaculum ruminis DSM 2154, Desulfotomaculum ruminis str. DSM 2154, Desulfotomaculum ruminis strain DSM 2154
Server load: low (12%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.