STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEG61713.1PFAM: Aldehyde Dehydrogenase; KEGG: ssm:Spirs_2638 aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (491 aa)    
Predicted Functional Partners:
AEG58904.1
PFAM: iron-containing alcohol dehydrogenase; Aldehyde Dehydrogenase; KEGG: drm:Dred_1495 bifunctional acetaldehyde-CoA/alcohol dehydrogenase; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.
  
 
 0.970
ackA
Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family.
  
 
 0.946
acsA
acetate/CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.
   
 0.934
AEG59707.1
PFAM: AMP-dependent synthetase and ligase; KEGG: tjr:TherJR_1681 AMP-dependent synthetase and ligase.
   
 0.934
AEG59654.1
PFAM: iron-containing alcohol dehydrogenase; KEGG: drm:Dred_2277 iron-containing alcohol dehydrogenase.
 
 
 0.928
AEG58833.1
PFAM: 6-phosphogluconate dehydrogenase NAD-binding; KEGG: bbe:BBR47_46110 putative dehydrogenase.
 
 
 0.927
AEG58383.1
PFAM: iron-containing alcohol dehydrogenase; KEGG: pca:Pcar_2847 alcohol dehydrogenase, class IV.
 
 
 0.924
AEG60059.1
Acetylornithine transaminase; KEGG: drm:Dred_2058 aminotransferase class-III; PFAM: aminotransferase class-III; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
 
 0.919
AEG60756.1
PFAM: Alcohol dehydrogenase GroES domain protein; Alcohol dehydrogenase zinc-binding domain protein; KEGG: ccb:Clocel_3267 alcohol dehydrogenase GroES domain-containing protein.
  
 0.913
AEG59988.1
KEGG: drm:Dred_2081 CoA-binding domain-containing protein; TIGRFAM: acetyl coenzyme A synthetase (ADP forming), alpha domain protein; PFAM: CoA-binding domain protein.
    
 0.906
Your Current Organism:
Desulfotomaculum ruminis
NCBI taxonomy Id: 696281
Other names: D. ruminis DSM 2154, Desulfotomaculum ruminis ATCC 23193, Desulfotomaculum ruminis DL, Desulfotomaculum ruminis DSM 2154, Desulfotomaculum ruminis str. DSM 2154, Desulfotomaculum ruminis strain DSM 2154
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