STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEG61726.1KEGG: pct:PC1_3262 hypothetical protein. (305 aa)    
Predicted Functional Partners:
AEG58435.1
KEGG: drm:Dred_0072 thiamine biosynthesis protein ThiS; TIGRFAM: thiamine biosynthesis protein ThiS; PFAM: thiamineS protein.
  
 
 0.919
iscS
Cysteine desulfurase NifS; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.
   
 0.826
AEG61722.1
PFAM: protein of unknown function DUF324; KEGG: cth:Cthe_3212 hypothetical protein.
       0.805
AEG61725.1
KEGG: cbb:CLD_2403 hypothetical protein.
       0.804
AEG61720.1
KEGG: cth:Cthe_3214 hypothetical protein.
       0.785
AEG61724.1
PFAM: protein of unknown function DUF324; KEGG: cth:Cthe_3210 hypothetical protein.
       0.784
thiG
Thiazole biosynthesis family protein; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
  
  
 0.776
AEG61723.1
PFAM: protein of unknown function DUF324; KEGG: cth:Cthe_3211 hypothetical protein.
       0.776
AEG61721.1
KEGG: cth:Cthe_3213 hypothetical protein.
       0.768
AEG59658.1
PFAM: thiamineS protein; KEGG: drm:Dred_2272 hypothetical protein.
  
 
 0.752
Your Current Organism:
Desulfotomaculum ruminis
NCBI taxonomy Id: 696281
Other names: D. ruminis DSM 2154, Desulfotomaculum ruminis ATCC 23193, Desulfotomaculum ruminis DL, Desulfotomaculum ruminis DSM 2154, Desulfotomaculum ruminis str. DSM 2154, Desulfotomaculum ruminis strain DSM 2154
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