Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
msrB_2Peptide methionine sulfoxide reductase MsrB. (163 aa)    
Predicted Functional Partners:
msrA_1
Peptide methionine sulfoxide reductase MsrA.
 
 0.987
msrA3
Peptide methionine sulfoxide reductase MsrA 3; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
 
 0.984
dsbD_2
Thiol:disulfide interchange protein DsbD precursor.
   
 
 0.779
rpoC
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
   0.656
grpE
Protein GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent i [...]
   
 
 0.603
nudC
NADH pyrophosphatase; Belongs to the Nudix hydrolase family.
 
      0.592
msrA_2
Peptide methionine sulfoxide reductase MsrA.
 
 
 0.576
rpmJ
50S ribosomal protein L36; Belongs to the bacterial ribosomal protein bL36 family.
    
 
 0.551
OJI92569.1
anti-sigma-K factor rskA.
       0.543
rplT
50S ribosomal protein L20; Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.
   
   0.517
Your Current Organism:
Planktotalea frisia
NCBI taxonomy Id: 696762
Other names: DSM 23709, LMG 25294, LMG:25294, P. frisia, Planktotalea frisia Hahnke et al. 2012, Rhodobacteraceae bacterium SH6-1, strain SH6-1
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