STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEE95228.1KEGG: tpd:Teth39_0005 hypothetical protein; SPTR: Putative uncharacterized protein. (97 aa)    
Predicted Functional Partners:
gyrB
DNA gyrase subunit B; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
  
    0.860
recF
DNA replication and repair protein RecF; The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP; Belongs to the RecF family.
  
    0.810
AEE96006.1
Septum formation initiator; InterPro IPR007060; KEGG: cac:CA_C3207 hypothetical protein; PFAM: Septum formation initiator; SPTR: Putative uncharacterized protein; PFAM: Septum formation initiator; TIGRFAM: cell division protein FtsL.
  
     0.693
AEE95226.1
DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]
  
    0.635
AEE97092.1
Membrane protein of unknown function; InterPro IPR007165; KEGG: clj:CLJU_c21840 hypothetical protein; PFAM: membrane protein of unknown function; SPTR: Putative uncharacterized protein; PFAM: Membrane protein of unknown function.
  
     0.587
dnaA
Chromosomal replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. Belongs to the DnaA family.
       0.575
gyrA
DNA gyrase subunit A; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
       0.552
AEE95640.1
Sporulation protein YtxC; InterPro IPR014199; KEGG: cth:Cthe_2071 hypothetical protein; PFAM: Sporulation protein YtxC; SPTR: Putative uncharacterized protein; PFAM: YtxC-like family; TIGRFAM: putative sporulation protein YtxC.
  
     0.528
AEE97801.1
Membrane protein of unknown function; InterPro IPR007165; KEGG: tpd:Teth39_1403 hypothetical protein; PFAM: membrane protein of unknown function; SPTR: Putative uncharacterized protein; PFAM: Membrane protein of unknown function.
  
     0.488
AEE96005.1
Spore cortex biosynthesis protein YabQ; InterPro IPR014242: IPR019074; KEGG: tjr:TherJR_0188 spore cortex biosynthesis protein YabQ; PFAM: Spore cortex biosynthesis protein, YabQ-like; SPTR: Spore cortex biosynthesis protein YabQ; TIGRFAM: spore cortex biosynthesis protein YabQ; PFAM: Spore cortex protein YabQ (Spore_YabQ); TIGRFAM: spore cortex biosynthesis protein YabQ.
  
     0.479
Your Current Organism:
Mahella australiensis
NCBI taxonomy Id: 697281
Other names: M. australiensis 50-1 BON, Mahella australiensis 50-1 BON, Mahella australiensis DSM 15567, Mahella australiensis str. 50-1 BON, Mahella australiensis strain 50-1 BON
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