AEE95361.1 protein (Mahella australiensis) - STRING interaction network

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Predicted Interactions

gene neighborhood

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AEE95361.1

Extracellular solute-binding protein family 1; COGs: COG1653 ABC-type sugar transport system periplasmic component; InterPro IPR006059; KEGG: gym:GYMC10_2462 extracellular solute-binding protein family 1; PFAM: extracellular solute-binding protein family 1; SPTR: Extracellular solute-binding protein family 1; PFAM: Bacterial extracellular solute-binding protein. (555 aa)

Predicted Functional Partners:

AEE95363.1

0.899

AEE95362.1

0.888

AEE95403.1

0.799

AEE96863.1

0.797

AEE96552.1

0.774

AEE96864.1

0.770

AEE96484.1

0.765

AEE97141.1

0.761

AEE95350.1

0.759

AEE96485.1

0.759

Your Current Organism:

Mahella australiensis

NCBI taxonomy Id: 697281
Other names: M. australiensis 50-1 BON, Mahella australiensis 50-1 BON, Mahella australiensis DSM 15567, Mahella australiensis str. 50-1 BON, Mahella australiensis strain 50-1 BON

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AEE95350.1	AEE95361.1	Mahau_0127	Mahau_0138	Carbohydrate ABC transporter membrane protein 1, CUT1 family; COGs: COG4209 ABC-type polysaccharide transport system permease component; InterPro IPR000515; KEGG: ate:Athe_2093 binding-protein-dependent transport systems inner membrane component; PFAM: binding-protein-dependent transport systems inner membrane component; SPTR: Binding-protein-dependent transport systems inner membrane component; PFAM: Binding-protein-dependent transport system inner membrane component.	Extracellular solute-binding protein family 1; COGs: COG1653 ABC-type sugar transport system periplasmic component; InterPro IPR006059; KEGG: gym:GYMC10_2462 extracellular solute-binding protein family 1; PFAM: extracellular solute-binding protein family 1; SPTR: Extracellular solute-binding protein family 1; PFAM: Bacterial extracellular solute-binding protein.	0.759
AEE95350.1	AEE95363.1	Mahau_0127	Mahau_0140	Carbohydrate ABC transporter membrane protein 1, CUT1 family; COGs: COG4209 ABC-type polysaccharide transport system permease component; InterPro IPR000515; KEGG: ate:Athe_2093 binding-protein-dependent transport systems inner membrane component; PFAM: binding-protein-dependent transport systems inner membrane component; SPTR: Binding-protein-dependent transport systems inner membrane component; PFAM: Binding-protein-dependent transport system inner membrane component.	COGs: COG0395 ABC-type sugar transport system permease component; InterPro IPR000515; KEGG: gym:GYMC10_4530 binding-protein-dependent transport systems inner membrane component; PFAM: binding-protein-dependent transport systems inner membrane component; SPTR: Binding-protein-dependent transport systems inner membrane component; PFAM: Binding-protein-dependent transport system inner membrane component.	0.805
AEE95350.1	AEE95403.1	Mahau_0127	Mahau_0180	Carbohydrate ABC transporter membrane protein 1, CUT1 family; COGs: COG4209 ABC-type polysaccharide transport system permease component; InterPro IPR000515; KEGG: ate:Athe_2093 binding-protein-dependent transport systems inner membrane component; PFAM: binding-protein-dependent transport systems inner membrane component; SPTR: Binding-protein-dependent transport systems inner membrane component; PFAM: Binding-protein-dependent transport system inner membrane component.	COGs: COG0395 ABC-type sugar transport system permease component; InterPro IPR000515; KEGG: gym:GYMC10_4787 binding-protein-dependent transport systems inner membrane component; PFAM: binding-protein-dependent transport systems inner membrane component; SPTR: Binding-protein-dependent transport systems inner membrane component; PFAM: Binding-protein-dependent transport system inner membrane component.	0.805
AEE95350.1	AEE96485.1	Mahau_0127	Mahau_1291	Carbohydrate ABC transporter membrane protein 1, CUT1 family; COGs: COG4209 ABC-type polysaccharide transport system permease component; InterPro IPR000515; KEGG: ate:Athe_2093 binding-protein-dependent transport systems inner membrane component; PFAM: binding-protein-dependent transport systems inner membrane component; SPTR: Binding-protein-dependent transport systems inner membrane component; PFAM: Binding-protein-dependent transport system inner membrane component.	COGs: COG0395 ABC-type sugar transport system permease component; InterPro IPR000515; KEGG: gym:GYMC10_2464 binding-protein-dependent transport systems inner membrane component; PFAM: binding-protein-dependent transport systems inner membrane component; SPTR: Binding-protein-dependent transport systems inner membrane component; PFAM: Binding-protein-dependent transport system inner membrane component.	0.804
AEE95350.1	AEE96552.1	Mahau_0127	Mahau_1358	Carbohydrate ABC transporter membrane protein 1, CUT1 family; COGs: COG4209 ABC-type polysaccharide transport system permease component; InterPro IPR000515; KEGG: ate:Athe_2093 binding-protein-dependent transport systems inner membrane component; PFAM: binding-protein-dependent transport systems inner membrane component; SPTR: Binding-protein-dependent transport systems inner membrane component; PFAM: Binding-protein-dependent transport system inner membrane component.	KEGG: pjd:Pjdr2_4182 binding-protein-dependent transport systems inner membrane component; SPTR: Binding-protein-dependent transport systems inner membrane component.	0.579
AEE95350.1	AEE96863.1	Mahau_0127	Mahau_1682	Carbohydrate ABC transporter membrane protein 1, CUT1 family; COGs: COG4209 ABC-type polysaccharide transport system permease component; InterPro IPR000515; KEGG: ate:Athe_2093 binding-protein-dependent transport systems inner membrane component; PFAM: binding-protein-dependent transport systems inner membrane component; SPTR: Binding-protein-dependent transport systems inner membrane component; PFAM: Binding-protein-dependent transport system inner membrane component.	COGs: COG0395 ABC-type sugar transport system permease component; InterPro IPR000515; KEGG: gym:GYMC10_2464 binding-protein-dependent transport systems inner membrane component; PFAM: binding-protein-dependent transport systems inner membrane component; SPTR: Binding-protein-dependent transport systems inner membrane component; PFAM: Binding-protein-dependent transport system inner membrane component.	0.804
AEE95361.1	AEE95350.1	Mahau_0138	Mahau_0127	Extracellular solute-binding protein family 1; COGs: COG1653 ABC-type sugar transport system periplasmic component; InterPro IPR006059; KEGG: gym:GYMC10_2462 extracellular solute-binding protein family 1; PFAM: extracellular solute-binding protein family 1; SPTR: Extracellular solute-binding protein family 1; PFAM: Bacterial extracellular solute-binding protein.	Carbohydrate ABC transporter membrane protein 1, CUT1 family; COGs: COG4209 ABC-type polysaccharide transport system permease component; InterPro IPR000515; KEGG: ate:Athe_2093 binding-protein-dependent transport systems inner membrane component; PFAM: binding-protein-dependent transport systems inner membrane component; SPTR: Binding-protein-dependent transport systems inner membrane component; PFAM: Binding-protein-dependent transport system inner membrane component.	0.759
AEE95361.1	AEE95362.1	Mahau_0138	Mahau_0139	Extracellular solute-binding protein family 1; COGs: COG1653 ABC-type sugar transport system periplasmic component; InterPro IPR006059; KEGG: gym:GYMC10_2462 extracellular solute-binding protein family 1; PFAM: extracellular solute-binding protein family 1; SPTR: Extracellular solute-binding protein family 1; PFAM: Bacterial extracellular solute-binding protein.	Carbohydrate ABC transporter membrane protein 1, CUT1 family; COGs: COG4209 ABC-type polysaccharide transport system permease component; InterPro IPR000515; KEGG: ate:Athe_2331 binding-protein-dependent transport systems inner membrane component; PFAM: binding-protein-dependent transport systems inner membrane component; SPTR: Binding-protein-dependent transport systems inner membrane component; PFAM: Binding-protein-dependent transport system inner membrane component.	0.888
AEE95361.1	AEE95363.1	Mahau_0138	Mahau_0140	Extracellular solute-binding protein family 1; COGs: COG1653 ABC-type sugar transport system periplasmic component; InterPro IPR006059; KEGG: gym:GYMC10_2462 extracellular solute-binding protein family 1; PFAM: extracellular solute-binding protein family 1; SPTR: Extracellular solute-binding protein family 1; PFAM: Bacterial extracellular solute-binding protein.	COGs: COG0395 ABC-type sugar transport system permease component; InterPro IPR000515; KEGG: gym:GYMC10_4530 binding-protein-dependent transport systems inner membrane component; PFAM: binding-protein-dependent transport systems inner membrane component; SPTR: Binding-protein-dependent transport systems inner membrane component; PFAM: Binding-protein-dependent transport system inner membrane component.	0.899
AEE95361.1	AEE95403.1	Mahau_0138	Mahau_0180	Extracellular solute-binding protein family 1; COGs: COG1653 ABC-type sugar transport system periplasmic component; InterPro IPR006059; KEGG: gym:GYMC10_2462 extracellular solute-binding protein family 1; PFAM: extracellular solute-binding protein family 1; SPTR: Extracellular solute-binding protein family 1; PFAM: Bacterial extracellular solute-binding protein.	COGs: COG0395 ABC-type sugar transport system permease component; InterPro IPR000515; KEGG: gym:GYMC10_4787 binding-protein-dependent transport systems inner membrane component; PFAM: binding-protein-dependent transport systems inner membrane component; SPTR: Binding-protein-dependent transport systems inner membrane component; PFAM: Binding-protein-dependent transport system inner membrane component.	0.799
AEE95361.1	AEE96484.1	Mahau_0138	Mahau_1290	Extracellular solute-binding protein family 1; COGs: COG1653 ABC-type sugar transport system periplasmic component; InterPro IPR006059; KEGG: gym:GYMC10_2462 extracellular solute-binding protein family 1; PFAM: extracellular solute-binding protein family 1; SPTR: Extracellular solute-binding protein family 1; PFAM: Bacterial extracellular solute-binding protein.	Carbohydrate ABC transporter membrane protein 1, CUT1 family; COGs: COG4209 ABC-type polysaccharide transport system permease component; InterPro IPR000515; KEGG: ate:Athe_2331 binding-protein-dependent transport systems inner membrane component; PFAM: binding-protein-dependent transport systems inner membrane component; SPTR: Binding-protein-dependent transport systems inner membrane component; PFAM: Binding-protein-dependent transport system inner membrane component.	0.765
AEE95361.1	AEE96485.1	Mahau_0138	Mahau_1291	Extracellular solute-binding protein family 1; COGs: COG1653 ABC-type sugar transport system periplasmic component; InterPro IPR006059; KEGG: gym:GYMC10_2462 extracellular solute-binding protein family 1; PFAM: extracellular solute-binding protein family 1; SPTR: Extracellular solute-binding protein family 1; PFAM: Bacterial extracellular solute-binding protein.	COGs: COG0395 ABC-type sugar transport system permease component; InterPro IPR000515; KEGG: gym:GYMC10_2464 binding-protein-dependent transport systems inner membrane component; PFAM: binding-protein-dependent transport systems inner membrane component; SPTR: Binding-protein-dependent transport systems inner membrane component; PFAM: Binding-protein-dependent transport system inner membrane component.	0.759
AEE95361.1	AEE96552.1	Mahau_0138	Mahau_1358	Extracellular solute-binding protein family 1; COGs: COG1653 ABC-type sugar transport system periplasmic component; InterPro IPR006059; KEGG: gym:GYMC10_2462 extracellular solute-binding protein family 1; PFAM: extracellular solute-binding protein family 1; SPTR: Extracellular solute-binding protein family 1; PFAM: Bacterial extracellular solute-binding protein.	KEGG: pjd:Pjdr2_4182 binding-protein-dependent transport systems inner membrane component; SPTR: Binding-protein-dependent transport systems inner membrane component.	0.774
AEE95361.1	AEE96863.1	Mahau_0138	Mahau_1682	Extracellular solute-binding protein family 1; COGs: COG1653 ABC-type sugar transport system periplasmic component; InterPro IPR006059; KEGG: gym:GYMC10_2462 extracellular solute-binding protein family 1; PFAM: extracellular solute-binding protein family 1; SPTR: Extracellular solute-binding protein family 1; PFAM: Bacterial extracellular solute-binding protein.	COGs: COG0395 ABC-type sugar transport system permease component; InterPro IPR000515; KEGG: gym:GYMC10_2464 binding-protein-dependent transport systems inner membrane component; PFAM: binding-protein-dependent transport systems inner membrane component; SPTR: Binding-protein-dependent transport systems inner membrane component; PFAM: Binding-protein-dependent transport system inner membrane component.	0.797
AEE95361.1	AEE96864.1	Mahau_0138	Mahau_1683	Extracellular solute-binding protein family 1; COGs: COG1653 ABC-type sugar transport system periplasmic component; InterPro IPR006059; KEGG: gym:GYMC10_2462 extracellular solute-binding protein family 1; PFAM: extracellular solute-binding protein family 1; SPTR: Extracellular solute-binding protein family 1; PFAM: Bacterial extracellular solute-binding protein.	Carbohydrate ABC transporter membrane protein 1, CUT1 family; COGs: COG4209 ABC-type polysaccharide transport system permease component; InterPro IPR000515; KEGG: pjd:Pjdr2_3654 binding-protein-dependent transport systems inner membrane component; PFAM: binding-protein-dependent transport systems inner membrane component; SPTR: Binding-protein-dependent transport systems inner membrane component; PFAM: Binding-protein-dependent transport system inner membrane component.	0.770
AEE95361.1	AEE97141.1	Mahau_0138	Mahau_1965	Extracellular solute-binding protein family 1; COGs: COG1653 ABC-type sugar transport system periplasmic component; InterPro IPR006059; KEGG: gym:GYMC10_2462 extracellular solute-binding protein family 1; PFAM: extracellular solute-binding protein family 1; SPTR: Extracellular solute-binding protein family 1; PFAM: Bacterial extracellular solute-binding protein.	Carbohydrate ABC transporter membrane protein 1, CUT1 family; COGs: COG4209 ABC-type polysaccharide transport system permease component; InterPro IPR000515; KEGG: gym:GYMC10_4742 binding-protein-dependent transport systems inner membrane component; PFAM: binding-protein-dependent transport systems inner membrane component; SPTR: Binding-protein-dependent transport systems inner membrane component; PFAM: Binding-protein-dependent transport system inner membrane component.	0.761
AEE95362.1	AEE95361.1	Mahau_0139	Mahau_0138	Carbohydrate ABC transporter membrane protein 1, CUT1 family; COGs: COG4209 ABC-type polysaccharide transport system permease component; InterPro IPR000515; KEGG: ate:Athe_2331 binding-protein-dependent transport systems inner membrane component; PFAM: binding-protein-dependent transport systems inner membrane component; SPTR: Binding-protein-dependent transport systems inner membrane component; PFAM: Binding-protein-dependent transport system inner membrane component.	Extracellular solute-binding protein family 1; COGs: COG1653 ABC-type sugar transport system periplasmic component; InterPro IPR006059; KEGG: gym:GYMC10_2462 extracellular solute-binding protein family 1; PFAM: extracellular solute-binding protein family 1; SPTR: Extracellular solute-binding protein family 1; PFAM: Bacterial extracellular solute-binding protein.	0.888
AEE95362.1	AEE95363.1	Mahau_0139	Mahau_0140	Carbohydrate ABC transporter membrane protein 1, CUT1 family; COGs: COG4209 ABC-type polysaccharide transport system permease component; InterPro IPR000515; KEGG: ate:Athe_2331 binding-protein-dependent transport systems inner membrane component; PFAM: binding-protein-dependent transport systems inner membrane component; SPTR: Binding-protein-dependent transport systems inner membrane component; PFAM: Binding-protein-dependent transport system inner membrane component.	COGs: COG0395 ABC-type sugar transport system permease component; InterPro IPR000515; KEGG: gym:GYMC10_4530 binding-protein-dependent transport systems inner membrane component; PFAM: binding-protein-dependent transport systems inner membrane component; SPTR: Binding-protein-dependent transport systems inner membrane component; PFAM: Binding-protein-dependent transport system inner membrane component.	0.944
AEE95362.1	AEE95403.1	Mahau_0139	Mahau_0180	Carbohydrate ABC transporter membrane protein 1, CUT1 family; COGs: COG4209 ABC-type polysaccharide transport system permease component; InterPro IPR000515; KEGG: ate:Athe_2331 binding-protein-dependent transport systems inner membrane component; PFAM: binding-protein-dependent transport systems inner membrane component; SPTR: Binding-protein-dependent transport systems inner membrane component; PFAM: Binding-protein-dependent transport system inner membrane component.	COGs: COG0395 ABC-type sugar transport system permease component; InterPro IPR000515; KEGG: gym:GYMC10_4787 binding-protein-dependent transport systems inner membrane component; PFAM: binding-protein-dependent transport systems inner membrane component; SPTR: Binding-protein-dependent transport systems inner membrane component; PFAM: Binding-protein-dependent transport system inner membrane component.	0.805
AEE95362.1	AEE96485.1	Mahau_0139	Mahau_1291	Carbohydrate ABC transporter membrane protein 1, CUT1 family; COGs: COG4209 ABC-type polysaccharide transport system permease component; InterPro IPR000515; KEGG: ate:Athe_2331 binding-protein-dependent transport systems inner membrane component; PFAM: binding-protein-dependent transport systems inner membrane component; SPTR: Binding-protein-dependent transport systems inner membrane component; PFAM: Binding-protein-dependent transport system inner membrane component.	COGs: COG0395 ABC-type sugar transport system permease component; InterPro IPR000515; KEGG: gym:GYMC10_2464 binding-protein-dependent transport systems inner membrane component; PFAM: binding-protein-dependent transport systems inner membrane component; SPTR: Binding-protein-dependent transport systems inner membrane component; PFAM: Binding-protein-dependent transport system inner membrane component.	0.804

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Network Stats

number of nodes:

7

number of edges:

8

average node degree:

2.29

avg. local clustering coefficient:

0.829

expected number of edges:

6

PPI enrichment p-value:

0.293

your network does not have significantly more
interactions than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0032446

Protein modification by small protein conjugation

9 of 195

1.86

4.35

8.06e-13

GO:0016567

Protein ubiquitination

8 of 176

1.85

4.05

1.13e-11

GO:0019941

Modification-dependent protein catabolic process

9 of 249

1.75

3.85

2.88e-12

GO:0006511

Ubiquitin-dependent protein catabolic process

8 of 241

1.71

3.42

9.55e-11

GO:0036211

Protein modification process

11 of 932

1.26

2.08

7.05e-12

(more ...)

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0031625

Ubiquitin protein ligase binding

4 of 31

2.3

2.63

8.04e-06

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0031461

cullin-RING ubiquitin ligase complex

5 of 54

2.16

3.29

1.56e-07

GO:0031463

Cul3-RING ubiquitin ligase complex

3 of 3

3.19

3.28

1.11e-06

GO:0019005

SCF ubiquitin ligase complex

3 of 22

2.33

2.11

9.49e-05

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:2915

Protein neddylation, and SCF ubiquitin ligase complex

8 of 24

2.72

8.54

1.14e-17

CL:2914

cullin-RING ubiquitin ligase complex, and COP9 signalosome

9 of 42

2.52

8.51

1.16e-18

CL:2918

Protein neddylation, and SCF ubiquitin ligase complex

7 of 19

2.76

7.62

1.53e-15

CL:2920

Mixed, incl. Nuclear SCF ubiquitin ligase complex, and Cullin

4 of 10

2.79

3.99

3.72e-08

CL:2923

Nuclear SCF ubiquitin ligase complex, and SKP1 component, POZ domain

2 of 5

2.79

1.41

0.0027

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map04120

Ubiquitin mediated proteolysis

8 of 131

1.98

4.85

3.81e-13

map04111

Cell cycle - yeast

5 of 156

1.7

2.29

2.34e-06

map04141

Protein processing in endoplasmic reticulum

5 of 221

1.55

1.92

8.49e-06

Reactome Pathways

pathway

description

count in network

strength

signal

false discovery rate

MAP-983168

Antigen processing: Ubiquitination & Proteasome degradation

6 of 148

1.8

2.77

2.04e-07

MAP-983169

Class I MHC mediated antigen processing & presentation

6 of 217

1.63

2.3

9.54e-07

MAP-1280218

Adaptive Immune System

6 of 301

1.49

1.91

4.32e-06

MAP-9020702

Interleukin-1 signaling

2 of 14

2.35

1.12

0.0086

MAP-446652

Interleukin-1 family signaling

2 of 14

2.35

1.12

0.0086

(more ...)

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0031461

cullin-RING ubiquitin ligase complex

6 of 65

2.16

4.06

1.88e-09

GOCC:0031463

Cul3-RING ubiquitin ligase complex

3 of 3

3.19

3.31

9.96e-07

GOCC:0017117

Single-stranded DNA-dependent ATP-dependent DNA helicase complex

3 of 3

3.19

3.31

9.96e-07

GOCC:0043291

RAVE complex

3 of 5

2.97

3.14

1.86e-06

GOCC:0019005

SCF ubiquitin ligase complex

3 of 37

2.1

1.86

0.00022

(more ...)

Protein Domains and Features (InterPro)

domain

description

count in network

strength

signal

false discovery rate

IPR045093

Cullin

3 of 4

3.07

2.57

2.20e-05

IPR001373

Cullin, N-terminal

3 of 5

2.97

2.56

2.20e-05

IPR016159

Cullin repeat-like-containing domain superfamily

3 of 6

2.89

2.55

2.20e-05

IPR019559

Cullin protein, neddylation domain

2 of 3

3.02

1.4

0.0030

IPR036317

Cullin homology domain superfamily

2 of 4

2.89

1.35

0.0036

(more ...)

Protein Domains (SMART)

domain

description

count in network

strength

signal

false discovery rate

SM00884

Cullin protein neddylation domain

2 of 3

3.02

1.6

0.0013

SM00182

Cullin

2 of 3

3.02

1.6

0.0013

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