STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEE95394.1COGs: COG0213 Thymidine phosphorylase; InterPro IPR018090: IPR017459: IPR000312: IPR013102: IPR 017872: IPR000053; KEGG: tit:Thit_0437 pyrimidine-nucleoside phosphorylase; PFAM: glycosyl transferase family 3; Glycosyl transferase, family 3-like; Pyrimidine nucleoside phosphorylase domain; PRIAM: Pyrimidine-nucleoside phosphorylase; SPTR: Pyrimidine-nucleoside phosphorylase; TIGRFAM: pyrimidine-nucleoside phosphorylase; PFAM: Glycosyl transferase family, a/b domain; Pyrimidine nucleoside phosphorylase C-terminal domain; Glycosyl transferase family, helical bundle domain; TIGRFAM: pyrimi [...] (441 aa)    
Predicted Functional Partners:
AEE96293.1
Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family.
 
 0.996
deoB
Phosphopentomutase; Phosphotransfer between the C1 and C5 carbon atoms of pentose; Belongs to the phosphopentomutase family.
 
 
 0.985
deoC
Deoxyribose-phosphate aldolase; Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5- phosphate; Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
 
 
 0.933
upp
Uracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate.
    
 0.929
AEE97902.1
CMP/dCMP deaminase zinc-binding protein; COGs: COG0295 Cytidine deaminase; InterPro IPR002125; KEGG: bcl:ABC0477 hypothetical protein; PFAM: CMP/dCMP deaminase zinc-binding; SPTR: Putative uncharacterized protein; PFAM: Cytidine and deoxycytidylate deaminase zinc-binding region.
  
 
 0.928
AEE97529.1
COGs: COG0572 Uridine kinase; KEGG: tte:TTE1778 uridine kinase; SPTR: Phosphoribulokinase/uridine kinase; PFAM: Phosphoribulokinase / Uridine kinase family.
    
 0.920
surE
5'-nucleotidase; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family.
    
 0.913
pyrR
Uracil phosphoribosyltransferase; Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant; Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily.
     
 0.913
AEE95393.1
Glycerol-1-phosphate dehydrogenase (NAD(P)(+)); COGs: COG0371 Glycerol dehydrogenase; InterPro IPR002658; KEGG: tit:Thit_1700 3-dehydroquinate synthase; PFAM: 3-dehydroquinate synthase; PRIAM: Glycerol-1-phosphate dehydrogenase (NAD(P)(+)); SPTR: 3-dehydroquinate synthase; PFAM: 3-dehydroquinate synthase.
       0.741
AEE95395.1
Protein of unknown function DUF214; InterPro IPR003838; KEGG: csc:Csac_0506 hypothetical protein; PFAM: protein of unknown function DUF214; SPTR: Putative uncharacterized protein; PFAM: Predicted permease.
       0.603
Your Current Organism:
Mahella australiensis
NCBI taxonomy Id: 697281
Other names: M. australiensis 50-1 BON, Mahella australiensis 50-1 BON, Mahella australiensis DSM 15567, Mahella australiensis str. 50-1 BON, Mahella australiensis strain 50-1 BON
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.