STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Gene Fusion
Cooccurrence
Coexpression
Experiments
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Textmining
[Homology]
Score
AEE95429.1Cobalamin synthesis protein P47K; COGs: COG0523 Putative GTPase (G3E family); InterPro IPR003495; KEGG: hor:Hore_15320 cobalamin synthesis protein P47K; PFAM: cobalamin synthesis protein P47K; SPTR: Cobalamin synthesis protein/P47K; PFAM: CobW/HypB/UreG, nucleotide-binding domain. (311 aa)    
Predicted Functional Partners:
AEE95428.1
COGs: COG0407 Uroporphyrinogen-III decarboxylase; InterPro IPR000257; KEGG: hor:Hore_15330 methylamine-specific methylcobalamin coenzyme M methyltransferase; PFAM: Uroporphyrinogen decarboxylase (URO-D); SPTR: Methylamine-specific methylcobalamin coenzyme M methyltransferase; PFAM: Uroporphyrinogen decarboxylase (URO-D); TIGRFAM: methyltransferase, MtaA/CmuA family; Belongs to the uroporphyrinogen decarboxylase family.
 
    0.943
AEE97917.1
Transcriptional regulator, ArsR family; COGs: COG0640 transcriptional regulator protein; InterPro IPR001845; KEGG: dae:Dtox_4284 transcriptional regulator, ArsR family; PFAM: regulatory protein ArsR; SMART: regulatory protein ArsR; SPTR: Transcriptional regulator, ArsR family; PFAM: Bacterial regulatory protein, arsR family.
    
 0.854
map
Methionine aminopeptidase, type I; Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed; Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
    
 
 0.790
hisI
COGs: COG0139 Phosphoribosyl-AMP cyclohydrolase; InterPro IPR008179: IPR002496: IPR021130; KEGG: tit:Thit_1813 phosphoribosyl-ATP diphosphatase; PFAM: phosphoribosyl-AMP cyclohydrolase; Phosphoribosyl-ATP pyrophosphohydrolase-like; SPTR: Phosphoribosyl-ATP diphosphatase; TIGRFAM: phosphoribosyl-ATP diphosphatase; PFAM: Phosphoribosyl-ATP pyrophosphohydrolase; Phosphoribosyl-AMP cyclohydrolase; TIGRFAM: phosphoribosyl-ATP pyrophosphohydrolase; In the N-terminal section; belongs to the PRA-CH family.
     
 0.748
rpsZ
Ribosomal protein S14; Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
  
 
 0.737
AEE97114.1
Periplasmic solute binding protein; COGs: COG0803 ABC-type metal ion transport system periplasmic component/surface adhesin; InterPro IPR006127: IPR006128: IPR006129; KEGG: tpd:Teth39_1924 periplasmic solute binding protein; PFAM: periplasmic solute binding protein; SPTR: Periplasmic solute binding protein; PFAM: Periplasmic solute binding protein family; Belongs to the bacterial solute-binding protein 9 family.
  
  
 0.650
AEE96227.1
Transcriptional regulator, TraR/DksA family; COGs: COG1734 DnaK suppressor protein; InterPro IPR000962: IPR014240; KEGG: amt:Amet_2798 TraR/DksA family transcriptional regulator; SPTR: Transcriptional regulator, TraR/DksA family; TIGRFAM: sporulation protein, yteA family; PFAM: Prokaryotic dksA/traR C4-type zinc finger; TIGRFAM: sporulation protein, yteA family; RNA polymerase-binding protein DksA.
  
  
 0.628
rpmB
COGs: COG0227 Ribosomal protein L28; InterPro IPR001383; KEGG: cbf:CLI_2559 50S ribosomal protein L28; PFAM: ribosomal protein L28; SPTR: 50S ribosomal protein L28; TIGRFAM: ribosomal protein L28; PFAM: Ribosomal L28 family; TIGRFAM: ribosomal protein L28; Belongs to the bacterial ribosomal protein bL28 family.
  
  
 0.620
AEE96282.1
Methyltransferase cognate corrinoid protein; COGs: COG5012 cobalamin binding protein; InterPro IPR003759: IPR006158: IPR012741; KEGG: dth:DICTH_0565 trimethylamine corrinoid protein 2; PFAM: cobalamin B12-binding domain protein; Methionine synthase B12-binding module cap domain protein; SPTR: Trimethylamine corrinoid protein 2; TIGRFAM: methyltransferase cognate corrinoid protein; PFAM: B12 binding domain; TIGRFAM: methyltransferase cognate corrinoid proteins, Methanosarcina family; methylmalonyl-CoA mutase C-terminal domain.
 
  
 0.601
AEE97861.1
COGs: COG0407 Uroporphyrinogen-III decarboxylase; InterPro IPR000257; KEGG: cbb:CLD_3055 putative methylcobalamin:coenzyme M methyltransferase; PFAM: Uroporphyrinogen decarboxylase (URO-D); SPTR: Uroporphyrinogen-III decarboxylase-like protein; PFAM: Uroporphyrinogen decarboxylase (URO-D); TIGRFAM: methyltransferase, MtaA/CmuA family; Belongs to the uroporphyrinogen decarboxylase family.
 
    0.552
Your Current Organism:
Mahella australiensis
NCBI taxonomy Id: 697281
Other names: M. australiensis 50-1 BON, Mahella australiensis 50-1 BON, Mahella australiensis DSM 15567, Mahella australiensis str. 50-1 BON, Mahella australiensis strain 50-1 BON
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