Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
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experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
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AEE95619.1Anti-sigma-factor antagonist; COGs: COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor); InterPro IPR003658: IPR014237: IPR002645; KEGG: bpf:BpOF4_14825 anti-sigma F factor antagonist (stage II sporulation protein AA); PFAM: Sulfate transporter/antisigma-factor antagonist STAS; SPTR: Anti-sigma factor antagonist; TIGRFAM: anti-sigma F factor antagonist; anti-anti-sigma factor; PFAM: STAS domain; TIGRFAM: anti-anti-sigma factor; anti-sigma F factor antagonist; Belongs to the anti-sigma-factor antagonist family. (119 aa)    
Predicted Functional Partners:
spoIIAB
Anti-sigma regulatory factor, serine/threonine protein kinase; Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti- anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition.
 
 
 0.997
AEE95621.1
RNA polymerase, sigma 28 subunit, SigF; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
 
  
 0.962
AEE96441.1
COGs: COG2172 Anti-sigma regulatory factor (Ser/Thr protein kinase); InterPro IPR003594; KEGG: csc:Csac_1856 putative anti-sigma regulatory factor, serine/threonine protein kinase; PFAM: ATP-binding region ATPase domain protein; SPTR: Putative anti-sigma regulatory factor, serine/threonine protein kinase; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase.
  
 
 0.824
AEE97030.1
Stage IV sporulation protein A; ATPase. Has a role at an early stage in the morphogenesis of the spore coat.
  
   
 0.751
AEE95816.1
Stage II sporulation protein E, protein serine/threonine phosphatase; COGs: COG2208 Serine phosphatase RsbU regulator of sigma subunit; InterPro IPR014221: IPR010822: IPR001932; KEGG: cth:Cthe_2681 serine phosphatase; PFAM: Stage II sporulation protein E; PRIAM: Phosphoprotein phosphatase; SMART: protein phosphatase 2C domain protein; SPTR: Serine phosphatase; TIGRFAM: stage II sporulation protein E; PFAM: Stage II sporulation protein E (SpoIIE); TIGRFAM: stage II sporulation protein E.
  
  
 0.741
AEE96369.1
Stage V sporulation protein AD; InterPro IPR010894: IPR000209: IPR001412; KEGG: tpd:Teth39_1125 stage V sporulation protein AD; PFAM: Stage V sporulation AD family protein; SPTR: Stage V sporulation AD family protein; TIGRFAM: stage V sporulation protein AD; PFAM: Stage V sporulation protein AD (SpoVAD); TIGRFAM: stage V sporulation protein AD.
 
   
 0.726
AEE96370.1
Stage V sporulation protein AE; InterPro IPR005562: IPR014204; KEGG: aoe:Clos_1789 sporulation stage V protein AE; PFAM: SpoVA protein; SPTR: Sporulation stage V protein AE; TIGRFAM: stage V sporulation protein AE; PFAM: SpoVA protein; TIGRFAM: stage V sporulation protein AE.
 
     0.712
AEE96368.1
Stage V sporulation protein AC; InterPro IPR005562: IPR014203; KEGG: cno:NT01CX_1807 stage V sporulation protein AC; PFAM: SpoVA protein; SPTR: Stage V sporulation protein AC; TIGRFAM: stage V sporulation protein AC; PFAM: SpoVA protein; TIGRFAM: stage V sporulation protein AC.
 
   
 0.701
AEE97251.1
InterPro IPR014202; KEGG: aoe:Clos_0291 sporulation stage II protein R; PFAM: Sporulation stage II protein R; SPTR: Sporulation stage II protein R; TIGRFAM: stage II sporulation protein R; PFAM: Stage II sporulation protein R (spore_II_R); TIGRFAM: stage II sporulation protein R.
  
   
 0.684
AEE96653.1
Sporulation transcriptional activator Spo0A; May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.
 
  
 0.663
Your Current Organism:
Mahella australiensis
NCBI taxonomy Id: 697281
Other names: M. australiensis 50-1 BON, Mahella australiensis 50-1 BON, Mahella australiensis DSM 15567, Mahella australiensis str. 50-1 BON, Mahella australiensis strain 50-1 BON
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