STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEE95652.1UvrB/UvrC protein; COGs: COG3880 Uncharacterized protein with conserved CXXC pairs; InterPro IPR001943; KEGG: tte:TTE2329 hypothetical protein; PFAM: UvrB/UvrC protein; SPTR: UvrB/UvrC protein; PFAM: UvrB/uvrC motif. (178 aa)    
Predicted Functional Partners:
mcsB
ATP:guanido phosphotransferase; Catalyzes the specific phosphorylation of arginine residues in proteins.
 
 
 0.999
AEE95651.1
Transcriptional repressor, CtsR; COGs: COG4463 Transcriptional repressor of class III stress genes; InterPro IPR008463; KEGG: cno:NT01CX_1084 transcription regulator CtsR; PFAM: Firmicute transcriptional repressor of class III stress genes; SPTR: Transcription regulator ctsR; PFAM: Firmicute transcriptional repressor of class III stress genes (CtsR); Belongs to the CtsR family.
 
  
 0.994
AEE95654.1
ATPase AAA-2 domain protein; COGs: COG0542 ATPase with chaperone activity ATP-binding subunit; InterPro IPR018368: IPR001270: IPR004176: IPR003959: IPR 001943: IPR013093: IPR019489: IPR003593; KEGG: tte:TTE2327 ATPase with chaperone activity, ATP-binding subunit; PFAM: ATPase AAA-2 domain protein; Clp domain protein; AAA ATPase central domain protein; UvrB/UvrC protein; Clp ATPase-like; SMART: AAA ATPase; SPTR: ATPases with chaperone activity, ATP-binding subunit; PFAM: AAA domain (Cdc48 subfamily); C-terminal, D2-small domain, of ClpB protein; Clp amino terminal domain; ATPase family [...]
 
  
 0.951
radA
DNA repair protein RadA; DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
  
    0.858
AEE95267.1
COGs: COG0394 Protein-tyrosine-phosphatase; InterPro IPR017867: IPR000106; KEGG: aoe:Clos_2574 protein tyrosine phosphatase; PFAM: Protein-tyrosine phosphatase, low molecular weight; SMART: Protein-tyrosine phosphatase, low molecular weight; SPTR: Protein tyrosine phosphatase; PFAM: Low molecular weight phosphotyrosine protein phosphatase.
  
  
 0.798
AEE97523.1
ATPase AAA-2 domain protein; COGs: COG0542 ATPase with chaperone activity ATP-binding subunit; InterPro IPR004176: IPR003959: IPR001943: IPR013093: IPR 019489: IPR001270: IPR018368: IPR003593; KEGG: tjr:TherJR_0243 ATPase AAA-2 domain protein; PFAM: ATPase AAA-2 domain protein; AAA ATPase central domain protein; Clp domain protein; UvrB/UvrC protein; Clp ATPase-like; SMART: AAA ATPase; SPTR: ATPase AAA-2 domain protein; PFAM: AAA domain (Cdc48 subfamily); C-terminal, D2-small domain, of ClpB protein; Clp amino terminal domain; ATPase family associated with various cellular activities ( [...]
  
  
 0.650
AEE96219.1
COGs: COG4956 Integral membrane protein (PIN domain superfamily); InterPro IPR002716: IPR006596: IPR002792; KEGG: amt:Amet_4507 PilT domain-containing protein; PFAM: PilT protein domain protein; SMART: Nucleotide binding protein PINc; SPTR: PilT protein domain protein; PFAM: PIN domain.
 
    0.524
AEE95649.1
Radical SAM domain protein; COGs: COG0502 Biotin synthase; InterPro IPR005244: IPR007197: IPR006638; KEGG: csc:Csac_0491 biotin synthase; PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB; SPTR: Biotin synthase; PFAM: Radical SAM superfamily.
       0.439
AEE95650.1
16S rRNA m(2)G 1207 methyltransferase; COGs: COG2813 16S RNA G1207 methylase RsmC; InterPro IPR007848; KEGG: cth:Cthe_2935 methyltransferase small; PFAM: methyltransferase small; SPTR: Methyltransferase small; PFAM: Methyltransferase small domain.
       0.439
ispDF
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; Bifunctional enzyme that catalyzes the formation of 4- diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D- erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C- methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF).
  
    0.411
Your Current Organism:
Mahella australiensis
NCBI taxonomy Id: 697281
Other names: M. australiensis 50-1 BON, Mahella australiensis 50-1 BON, Mahella australiensis DSM 15567, Mahella australiensis str. 50-1 BON, Mahella australiensis strain 50-1 BON
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