Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AEE95699.11-Cys peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides. (220 aa)    
Predicted Functional Partners:
AEE97920.1
InterPro IPR005243; KEGG: dae:Dtox_4282 redox-active disulfide protein 2; SPTR: Redox-active disulfide protein 2; TIGRFAM: redox-active disulfide protein 2; TIGRFAM: small redox-active disulfide protein 2.
  
 0.963
AEE96935.1
FAD-dependent pyridine nucleotide-disulfide oxidoreductase; COGs: COG0492 Thioredoxin reductase; InterPro IPR000103: IPR013027; KEGG: cbi:CLJ_B3741 tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; SPTR: tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA; PFAM: Pyridine nucleotide-disulphide oxidoreductase.
  
 
 0.882
dnaK
Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.
   
 
 0.827
AEE95643.1
FAD-dependent pyridine nucleotide-disulfide oxidoreductase; COGs: COG0492 Thioredoxin reductase; InterPro IPR001412: IPR013027: IPR000103; KEGG: ctc:CTC02435 sarcosine oxidase alpha subunit; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; SPTR: Sarcosine oxidase alpha subunit; PFAM: Pyridine nucleotide-disulphide oxidoreductase.
  
 
 0.792
AEE95926.1
InterPro IPR003953; KEGG: cbe:Cbei_4529 pyridine nucleotide-disulphide oxidoreductase; PFAM: fumarate reductase/succinate dehydrogenase flavoprotein domain protein; SPTR: Pyridine nucleotide-disulphide oxidoreductase; PFAM: FAD dependent oxidoreductase.
  
 
 0.792
AEE97556.1
KEGG: tpd:Teth39_0044 StbA family protein; SPTR: StbA family protein; PFAM: StbA protein.
   
 
 0.780
AEE96591.1
COGs: COG0469 Pyruvate kinase; InterPro IPR015793: IPR015794: IPR008279: IPR018209: IPR 001697; KEGG: tte:TTE1815 pyruvate kinase; PFAM: Pyruvate kinase barrel; Pyruvate kinase alpha/beta; PEP-utilising protein mobile region; SPTR: Pyruvate kinase; TIGRFAM: pyruvate kinase; PFAM: Pyruvate kinase, barrel domain; PEP-utilising enzyme, mobile domain; Pyruvate kinase, alpha/beta domain; TIGRFAM: pyruvate kinase; Belongs to the pyruvate kinase family.
   
 
 0.746
AEE97187.1
ATP-dependent DNA helicase, RecQ family; COGs: COG0514 Superfamily II DNA helicase; InterPro IPR018329: IPR011545: IPR001650: IPR014021: IPR 014001; KEGG: caa:Caka_2440 ATP-dependent DNA helicase, RecQ family; PFAM: DEAD/DEAH box helicase domain protein; helicase domain protein; SMART: helicase domain protein; DEAD-like helicase; SPTR: ATP-dependent DNA helicase, RecQ family; TIGRFAM: ATP-dependent DNA helicase, RecQ family; PFAM: Helicase conserved C-terminal domain; DEAD/DEAH box helicase; TIGRFAM: ATP-dependent DNA helicase, RecQ family.
    
   0.738
AEE96113.1
Phosphodiesterase, MJ0936 family; COGs: COG0622 phosphoesterase; InterPro IPR000979: IPR004843: IPR020935; KEGG: pth:PTH_0793 phosphoesterase; PFAM: metallophosphoesterase; SPTR: Predicted phosphoesterase; TIGRFAM: phosphodiesterase, MJ0936 family; PFAM: Calcineurin-like phosphoesterase; TIGRFAM: phosphoesterase, MJ0936 family.
   
 
 0.697
AEE95260.1
FAD-dependent pyridine nucleotide-disulfide oxidoreductase; COGs: COG0446 NAD(FAD)-dependent dehydrogenase; InterPro IPR001763: IPR013027: IPR004099: IPR001455: IPR 003787; KEGG: cce:Ccel_1144 FAD-dependent pyridine nucleotide-disulphide oxidoreductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; pyridine nucleotide-disulphide oxidoreductase dimerisation region; Rhodanese domain protein; SirA-like domain-containing protein; DsrE family protein; SMART: Rhodanese domain protein; SPTR: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; PFAM: Pyridine nucle [...]
  
  
 0.692
Your Current Organism:
Mahella australiensis
NCBI taxonomy Id: 697281
Other names: M. australiensis 50-1 BON, Mahella australiensis 50-1 BON, Mahella australiensis DSM 15567, Mahella australiensis str. 50-1 BON, Mahella australiensis strain 50-1 BON
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.