STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AEE95715.1UvrD/REP helicase; ATP-dependent DNA helicase; Belongs to the helicase family. UvrD subfamily. (993 aa)    
Predicted Functional Partners:
AEE95714.1
Hypothetical protein; COGs: COG3857 ATP-dependent nuclease subunit B; KEGG: afn:Acfer_1333 ATP-dependent nuclease subunit B-like protein; SPTR: ATP-dependent nuclease subunit B-like protein.
 
 
 0.998
recD2
ATP-dependent DNA helicase, RecD/TraA family; DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity; Belongs to the RecD family. RecD-like subfamily.
  
 
 0.796
AEE97685.1
AAA ATPase; COGs: COG0507 ATP-dependent exoDNAse (exonuclease V) alpha subunit - helicase superfamily I member; InterPro IPR003593; KEGG: cth:Cthe_2249 ATP-dependent RecD/TraA family DNA helicase; SMART: AAA ATPase; SPTR: Helicase, RecD/TraA family; PFAM: Viral (Superfamily 1) RNA helicase; TIGRFAM: helicase, putative, RecD/TraA family.
  
 
 0.796
AEE96901.1
COGs: COG0210 Superfamily I DNA and RNA helicase; InterPro IPR014016: IPR014017: IPR000212: IPR005751; KEGG: tex:Teth514_0537 ATP-dependent DNA helicase PcrA; PFAM: UvrD/REP helicase; SPTR: ATP-dependent DNA helicase PcrA; TIGRFAM: ATP-dependent DNA helicase PcrA; PFAM: UvrD/REP helicase; TIGRFAM: ATP-dependent DNA helicase PcrA.
 
  
0.746
pheT
COGs: COG0072 Phenylalanyl-tRNA synthetase beta subunit; InterPro IPR002547: IPR005121: IPR004532: IPR005146: IPR 005147; KEGG: cth:Cthe_0215 phenylalanyl-tRNA synthetase subunit beta; PFAM: B3/4 domain protein; t-RNA-binding domain-containing protein; tRNA synthetase B5; ferredoxin-fold anticodon-binding; PRIAM: Phenylalanine--tRNA ligase; SPTR: Phenylalanyl-tRNA synthetase beta subunit; TIGRFAM: phenylalanyl-tRNA synthetase, beta subunit; PFAM: tRNA synthetase B5 domain; B3/4 domain; Ferredoxin-fold anticodon binding domain; Putative tRNA binding domain; TIGRFAM: phenylalanyl-tRNA sy [...]
     
 0.661
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
     
 0.622
recA
recA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family.
  
 
 0.599
ruvA
Holliday junction DNA helicase RuvA; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.
    
 0.598
recR
DNA replication and repair protein RecR; May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.
 
   
 0.578
AEE97044.1
DNA polymerase III catalytic subunit, DnaE type; COGs: COG0587 DNA polymerase III alpha subunit; InterPro IPR004805: IPR004013: IPR011708: IPR004365: IPR 003141; KEGG: tte:TTE1818 DNA polymerase III DnaE; PFAM: DNA polymerase III alpha subunit; PHP domain protein; nucleic acid binding OB-fold tRNA/helicase-type; PRIAM: DNA-directed DNA polymerase; SMART: phosphoesterase PHP domain protein; SPTR: DNA polymerase III alpha subunit; TIGRFAM: DNA polymerase III, alpha subunit; PFAM: Bacterial DNA polymerase III alpha subunit; PHP domain; OB-fold nucleic acid binding domain; TIGRFAM: DNA-dir [...]
 
  
 0.536
Your Current Organism:
Mahella australiensis
NCBI taxonomy Id: 697281
Other names: M. australiensis 50-1 BON, Mahella australiensis 50-1 BON, Mahella australiensis DSM 15567, Mahella australiensis str. 50-1 BON, Mahella australiensis strain 50-1 BON
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