STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
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Gene Fusion
Cooccurrence
Coexpression
Experiments
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Textmining
[Homology]
Score
AEE95854.1Homocysteine S-methyltransferase; COGs: COG0646 Methionine synthase I (cobalamin-dependent) methyltransferase domain; InterPro IPR003726; KEGG: tit:Thit_1600 homocysteine S-methyltransferase; PFAM: homocysteine S-methyltransferase; SPTR: Homocysteine S-methyltransferase; PFAM: Homocysteine S-methyltransferase. (413 aa)    
Predicted Functional Partners:
AEE96281.1
COGs: COG1410 Methionine synthase I cobalamin-binding domain; InterPro IPR000489; KEGG: tjr:TherJR_0059 dihydropteroate synthase DhpS; PFAM: dihydropteroate synthase DHPS; PRIAM: Methionine synthase; SPTR: Dihydropteroate synthase DHPS; PFAM: Pterin binding enzyme.
  
 0.984
AEE96282.1
Methyltransferase cognate corrinoid protein; COGs: COG5012 cobalamin binding protein; InterPro IPR003759: IPR006158: IPR012741; KEGG: dth:DICTH_0565 trimethylamine corrinoid protein 2; PFAM: cobalamin B12-binding domain protein; Methionine synthase B12-binding module cap domain protein; SPTR: Trimethylamine corrinoid protein 2; TIGRFAM: methyltransferase cognate corrinoid protein; PFAM: B12 binding domain; TIGRFAM: methyltransferase cognate corrinoid proteins, Methanosarcina family; methylmalonyl-CoA mutase C-terminal domain.
  
 0.979
AEE96091.1
COGs: COG0685 5 10-methylenetetrahydrofolate reductase; InterPro IPR003171; KEGG: slp:Slip_1393 methylenetetrahydrofolate reductase; PFAM: methylenetetrahydrofolate reductase; SPTR: Methylenetetrahydrofolate reductase; PFAM: Methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family.
 
  
 0.952
AEE95855.1
COGs: COG4585 Signal transduction histidine kinase; InterPro IPR005467: IPR003594: IPR004358: IPR016381: IPR 008595: IPR011712; KEGG: cth:Cthe_1268 histidine kinase; PFAM: Sensor DegS domain protein; histidine kinase dimerisation and phosphoacceptor region; ATP-binding region ATPase domain protein; SMART: ATP-binding region ATPase domain protein; SPTR: Histidine kinase; PFAM: Sensor protein DegS; Histidine kinase; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase.
       0.741
AEE95856.1
Two component transcriptional regulator, LuxR family; COGs: COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain; InterPro IPR000792: IPR001789; KEGG: cth:Cthe_1267 two component LuxR family transcriptional regulator; PFAM: response regulator receiver; regulatory protein LuxR; SMART: response regulator receiver; regulatory protein LuxR; SPTR: Two component transcriptional regulator, LuxR family; PFAM: Response regulator receiver domain; Bacterial regulatory proteins, luxR family.
       0.741
AEE96283.1
InterPro IPR004223; KEGG: tte:TTE1028 hypothetical protein; PFAM: Vitamin B12 dependent methionine synthase activation region; SPTR: Vitamin B12 dependent methionine synthase activation region; PFAM: Vitamin B12 dependent methionine synthase, activation domain.
 
  
 0.699
AEE95857.1
Auxin Efflux Carrier; COGs: COG0679 permease; InterPro IPR004776; KEGG: ssp:SSP0142 putative permease; PFAM: Auxin Efflux Carrier; SPTR: Putative permease; PFAM: Membrane transport protein.
       0.638
AEE95476.1
Homocysteine S-methyltransferase; COGs: COG0646 Methionine synthase I (cobalamin-dependent) methyltransferase domain; InterPro IPR003726: IPR003171; KEGG: csc:Csac_1165 bifunctional homocysteine S-methyltransferase/5,10-methylenetetrahydrofolate reductase protein; PFAM: homocysteine S-methyltransferase; methylenetetrahydrofolate reductase; SPTR: Methylenetetrahydrofolate reductase; PFAM: Methylenetetrahydrofolate reductase; Homocysteine S-methyltransferase.
 
  
0.637
AEE95853.1
Hypothetical protein; KEGG: tte:TTE0116 S-layer-like domain-containing protein; SPTR: Putative uncharacterized protein.
       0.523
AEE96722.1
Hypothetical protein; KEGG: bvu:BVU_2930 trimethylamine corrinoid protein 2; SPTR: B12 binding domain./Pterin binding enzyme.
 
    0.479
Your Current Organism:
Mahella australiensis
NCBI taxonomy Id: 697281
Other names: M. australiensis 50-1 BON, Mahella australiensis 50-1 BON, Mahella australiensis DSM 15567, Mahella australiensis str. 50-1 BON, Mahella australiensis strain 50-1 BON
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