Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AEE95855.1COGs: COG4585 Signal transduction histidine kinase; InterPro IPR005467: IPR003594: IPR004358: IPR016381: IPR 008595: IPR011712; KEGG: cth:Cthe_1268 histidine kinase; PFAM: Sensor DegS domain protein; histidine kinase dimerisation and phosphoacceptor region; ATP-binding region ATPase domain protein; SMART: ATP-binding region ATPase domain protein; SPTR: Histidine kinase; PFAM: Sensor protein DegS; Histidine kinase; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase. (388 aa)    
Predicted Functional Partners:
AEE95856.1
Two component transcriptional regulator, LuxR family; COGs: COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain; InterPro IPR000792: IPR001789; KEGG: cth:Cthe_1267 two component LuxR family transcriptional regulator; PFAM: response regulator receiver; regulatory protein LuxR; SMART: response regulator receiver; regulatory protein LuxR; SPTR: Two component transcriptional regulator, LuxR family; PFAM: Response regulator receiver domain; Bacterial regulatory proteins, luxR family.
 
 0.996
AEE96848.1
MCP methyltransferase, CheR-type; COGs: COG1352 Methylase of chemotaxis methyl-accepting protein; InterPro IPR000780; KEGG: cth:Cthe_0717 MCP methyltransferase, CheR-type; PFAM: MCP methyltransferase CheR-type; PRIAM: Protein-glutamate O-methyltransferase; SMART: MCP methyltransferase CheR-type; SPTR: MCP methyltransferase, CheR-type; PFAM: CheR methyltransferase, SAM binding domain; CheR methyltransferase, all-alpha domain.
      0.776
AEE95854.1
Homocysteine S-methyltransferase; COGs: COG0646 Methionine synthase I (cobalamin-dependent) methyltransferase domain; InterPro IPR003726; KEGG: tit:Thit_1600 homocysteine S-methyltransferase; PFAM: homocysteine S-methyltransferase; SPTR: Homocysteine S-methyltransferase; PFAM: Homocysteine S-methyltransferase.
       0.741
AEE95857.1
Auxin Efflux Carrier; COGs: COG0679 permease; InterPro IPR004776; KEGG: ssp:SSP0142 putative permease; PFAM: Auxin Efflux Carrier; SPTR: Putative permease; PFAM: Membrane transport protein.
       0.664
AEE95505.1
Transcriptional regulator, LuxR family; COGs: COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain; InterPro IPR000792; KEGG: gsu:GSU2670 LuxR family transcriptional regulator; PFAM: regulatory protein LuxR; SMART: regulatory protein LuxR; SPTR: Transcriptional regulator, LuxR family; PFAM: Bacterial regulatory proteins, luxR family.
  
 
 0.593
AEE96796.1
Hypothetical protein; KEGG: swo:Swol_1080 ATP-dependent transcriptional regulator-like protein; SPTR: Putative uncharacterized protein.
  
 
 0.593
AEE95584.1
Protein of unknown function DUF327; COGs: COG1728 conserved hypothetical protein; InterPro IPR005585; KEGG: tpd:Teth39_2148 hypothetical protein; PFAM: protein of unknown function DUF327; SPTR: Putative uncharacterized protein; PFAM: Protein of unknown function (DUF327).
 
     0.591
AEE97516.1
FlgN family protein; InterPro IPR007809; KEGG: cth:Cthe_2245 hypothetical protein; PFAM: FlgN family protein; SPTR: Putative uncharacterized protein; PFAM: FlgN protein.
  
     0.566
AEE97518.1
Flagellar operon protein YvyF; InterPro IPR022258; KEGG: aoe:Clos_2524 hypothetical protein; SPTR: Putative uncharacterized protein; TIGRFAM: Flagellar operon protein YvyF; TIGRFAM: flagellar operon protein TIGR03826.
 
     0.553
AEE96075.1
Type IV pilus assembly PilZ; COGs: COG5581 glycosyltransferase; InterPro IPR009875; KEGG: cth:Cthe_0488 type IV pilus assembly PilZ; PFAM: type IV pilus assembly PilZ; SPTR: Type IV pilus assembly PilZ; PFAM: PilZ domain.
 
  
 0.532
Your Current Organism:
Mahella australiensis
NCBI taxonomy Id: 697281
Other names: M. australiensis 50-1 BON, Mahella australiensis 50-1 BON, Mahella australiensis DSM 15567, Mahella australiensis str. 50-1 BON, Mahella australiensis strain 50-1 BON
Server load: low (16%) [HD]