Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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AEE95881.1DNA internalization-related competence protein ComEC/Rec2; COGs: COG2333 hydrolase (metallo-beta-lactamase superfamily); InterPro IPR004797: IPR004477: IPR004365; KEGG: cth:Cthe_0606 DNA internalization-related competence protein ComEC/Rec2; PFAM: ComEC/Rec2-related protein; nucleic acid binding OB-fold tRNA/helicase-type; SPTR: DNA internalization-related competence protein ComEC/Rec2; TIGRFAM: DNA internalization-related competence protein ComEC/Rec2; ComEC/Rec2-related protein; PFAM: Competence protein; Metallo-beta-lactamase superfamily; TIGRFAM: ComEC/Rec2-related protein; DNA int [...] (769 aa)    
Predicted Functional Partners:
AEE95882.1
COGs: COG1466 DNA polymerase III delta subunit; InterPro IPR005790: IPR010372; KEGG: tjr:TherJR_2462 DNA polymerase III, delta subunit; PFAM: DNA polymerase III delta; SPTR: DNA-directed DNA polymerase III delta subunit; TIGRFAM: DNA polymerase III, delta subunit; PFAM: DNA polymerase III, delta subunit; TIGRFAM: DNA polymerase III, delta subunit.
 
   
 0.919
AEE96041.1
DNA protecting protein DprA; COGs: COG0758 Rossmann fold nucleotide-binding protein involved in DNA uptake; InterPro IPR003488; KEGG: hmo:HM1_2210 DNA processing protein dpra, putative; PFAM: SMF family protein; SPTR: DNA protecting protein DprA; TIGRFAM: DNA protecting protein DprA; PFAM: DNA recombination-mediator protein A; TIGRFAM: DNA protecting protein DprA.
 
  
 0.915
AEE97519.1
COGs: COG1040 amidophosphoribosyltransferase; InterPro IPR000836; KEGG: tpd:Teth39_1788 phosphoribosyltransferase; PFAM: phosphoribosyltransferase; SPTR: Phosphoribosyltransferase; PFAM: Phosphoribosyl transferase domain; TIGRFAM: comF family protein.
 
  
 0.877
AEE96481.1
Competence protein ComEA helix-hairpin-helix repeat protein; COGs: COG1555 DNA uptake protein and related DNA-binding protein; InterPro IPR019554: IPR000445: IPR003583: IPR004509; KEGG: tpd:Teth39_1421 helix-hairpin-helix repeat-containing competence protein ComEA; PFAM: Soluble ligand binding domain; helix-hairpin-helix motif; SMART: Helix-hairpin-helix DNA-binding class 1; SPTR: Competence protein ComEA helix-hairpin-helix repeat protein; TIGRFAM: competence protein ComEA helix-hairpin-helix repeat protein; PFAM: Helix-hairpin-helix motif; SLBB domain; TIGRFAM: competence protein Com [...]
 
  
 0.829
AEE95880.1
Beta-lactamase-like protein; COGs: COG1234 Metal-dependent hydrolase of the beta-lactamase superfamily III; InterPro IPR000684; KEGG: cth:Cthe_3155 beta-lactamase-like protein; SPTR: Beta-lactamase-like protein; PFAM: Metallo-beta-lactamase superfamily.
       0.803
AEE96264.1
Mg chelatase, subunit ChlI; COGs: COG0606 ATPase with chaperone activity; InterPro IPR000523: IPR003593: IPR004482; KEGG: tpd:Teth39_1270 Mg chelatase, subunit ChlI; PFAM: magnesium chelatase ChlI subunit; SMART: AAA ATPase; SPTR: Mg chelatase, subunit ChlI; TIGRFAM: Mg chelatase, subunit ChlI; PFAM: Magnesium chelatase, subunit ChlI; Lon protease (S16) C-terminal proteolytic domain; TIGRFAM: Mg chelatase-related protein.
 
  
 0.770
AEE95884.1
Holliday junction resolvase YqgF; Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA; Belongs to the YqgF HJR family.
       0.760
AEE96330.1
Type II secretion system F domain protein; COGs: COG1459 Type II secretory pathway component PulF; InterPro IPR018076: IPR001992: IPR003004; KEGG: amt:Amet_3480 type II secretion system protein; PFAM: Type II secretion system F domain; SPTR: Type II secretion system protein; PFAM: Bacterial type II secretion system protein F domain.
  
  
 0.755
AEE96331.1
Prepilin peptidase; Cleaves type-4 fimbrial leader sequence and methylates the N- terminal (generally Phe) residue.
  
  
 0.750
AEE97557.1
Peptidase A24A prepilin type IV; InterPro IPR000045; KEGG: tte:TTE2059 hypothetical protein; PFAM: peptidase A24A prepilin type IV; SPTR: Putative uncharacterized protein; PFAM: Type IV leader peptidase family.
  
  
 0.750
Your Current Organism:
Mahella australiensis
NCBI taxonomy Id: 697281
Other names: M. australiensis 50-1 BON, Mahella australiensis 50-1 BON, Mahella australiensis DSM 15567, Mahella australiensis str. 50-1 BON, Mahella australiensis strain 50-1 BON
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