STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
cobDCobalamin biosynthesis protein CobD; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group. (313 aa)    
Predicted Functional Partners:
cobQ
Cobyric acid synthase CobQ; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily.
 
 0.999
AEE95957.1
Aminotransferase class I and II; COGs: COG0079 Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase; InterPro IPR004839; KEGG: amt:Amet_3614 threonine-phosphate decarboxylase; PFAM: aminotransferase class I and II; SPTR: Putative L-threonine-O-3-phosphate decarboxylase; PFAM: Aminotransferase class I and II; TIGRFAM: L-threonine-O-3-phosphate decarboxylase; histidinol-phosphate aminotransferase.
  
 0.996
AEE96297.1
Adenosylcobinamide-phosphateguanylyltransferase; COGs: COG2087 Adenosyl cobinamide kinase/adenosyl cobinamide phosphate guanylyltransferase; InterPro IPR003203; KEGG: tmt:Tmath_0418 adenosylcobinamide-phosphate guanylyltransferase; PFAM: cobalbumin biosynthesis protein; PRIAM: Adenosylcobinamide-phosphate guanylyltransferase; SPTR: Adenosylcobinamide-phosphate guanylyltransferase; PFAM: Cobinamide kinase / cobinamide phosphate guanyltransferase.
 
 
 0.994
AEE96592.1
cob(I)yrinic acid a,c-diamide adenosyltransferase; COGs: COG2109 ATP:corrinoid adenosyltransferase; InterPro IPR003724; KEGG: tte:TTE0370 ATP:corrinoid adenosyltransferase; PFAM: ATP:corrinoid adenosyltransferase BtuR/CobO/CobP; SPTR: ATP:corrinoid adenosyltransferase; PFAM: ATP:corrinoid adenosyltransferase BtuR/CobO/CobP; TIGRFAM: cob(I)alamin adenosyltransferase.
 
  
 0.971
cobS
Cobalamin 5'-phosphate synthase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family.
  
 0.953
cbiA
Cobyrinic acid a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family.
  
 0.934
cobT
Nicotinate-nucleotide/dimethylbenzimidazole phosphoribosyltransferase; Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB).
 
  
 0.915
AEE96421.1
Precorrin-8X methylmutase CbiC/CobH; COGs: COG2082 Precorrin isomerase; InterPro IPR003722; KEGG: tmt:Tmath_0421 precorrin-8X methylmutase; PFAM: Precorrin-8X methylmutase CbiC/CobH; SPTR: Precorrin-8X methylmutase; PFAM: Precorrin-8X methylmutase.
 
  
 0.915
AEE95958.1
GHMP kinase; COGs: COG4542 Protein involved in propanediol utilization and related protein (includes coumermycin biosynthetic protein) possible kinase; InterPro IPR012363: IPR006204: IPR013750; KEGG: amt:Amet_0068 GHMP kinase; PFAM: GHMP kinase; GHMP kinase domain protein; SPTR: Putative uncharacterized protein; PFAM: GHMP kinases N terminal domain.
     
 0.910
AEE95954.1
ABC transporter related protein; COGs: COG1120 ABC-type cobalamin/Fe3+-siderophores transport systems ATPase components; InterPro IPR003439: IPR003593: IPR017871; KEGG: tte:TTE0374 ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components; PFAM: ABC transporter related; SMART: AAA ATPase; SPTR: ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components; PFAM: ABC transporter.
 
   
 0.869
Your Current Organism:
Mahella australiensis
NCBI taxonomy Id: 697281
Other names: M. australiensis 50-1 BON, Mahella australiensis 50-1 BON, Mahella australiensis DSM 15567, Mahella australiensis str. 50-1 BON, Mahella australiensis strain 50-1 BON
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