| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AEE95470.1 | AEE95962.1 | Mahau_0252 | Mahau_0763 | CMP/dCMP deaminase zinc-binding protein; COGs: COG2131 Deoxycytidylate deaminase; InterPro IPR002125: IPR016192: IPR016473; KEGG: chy:CHY_2556 putative ComE operon protein 2; PFAM: CMP/dCMP deaminase zinc-binding; SPTR: Putative comE operon protein 2; PFAM: Cytidine and deoxycytidylate deaminase zinc-binding region. | Peptidase M24; COGs: COG0006 Xaa-Pro aminopeptidase; InterPro IPR000587: IPR000994: IPR001131; KEGG: tte:TTE1280 Xaa-Pro aminopeptidase; PFAM: peptidase M24; creatinase; SPTR: Xaa-Pro aminopeptidase; PFAM: Metallopeptidase family M24; Creatinase/Prolidase N-terminal domain; Belongs to the peptidase M24B family. | 0.664 |
| AEE95545.1 | AEE95962.1 | Mahau_0329 | Mahau_0763 | Dipeptidase; COGs: COG0624 Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylase; InterPro IPR001261: IPR010964: IPR002933: IPR011650; KEGG: hor:Hore_08190 Xaa-His dipeptidase; PFAM: peptidase M20; peptidase dimerisation domain protein; SPTR: Xaa-His dipeptidase; TIGRFAM: dipeptidase; PFAM: Peptidase family M20/M25/M40; Peptidase dimerisation domain; TIGRFAM: dipeptidase, putative. | Peptidase M24; COGs: COG0006 Xaa-Pro aminopeptidase; InterPro IPR000587: IPR000994: IPR001131; KEGG: tte:TTE1280 Xaa-Pro aminopeptidase; PFAM: peptidase M24; creatinase; SPTR: Xaa-Pro aminopeptidase; PFAM: Metallopeptidase family M24; Creatinase/Prolidase N-terminal domain; Belongs to the peptidase M24B family. | 0.537 |
| AEE95545.1 | guaB | Mahau_0329 | Mahau_1974 | Dipeptidase; COGs: COG0624 Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylase; InterPro IPR001261: IPR010964: IPR002933: IPR011650; KEGG: hor:Hore_08190 Xaa-His dipeptidase; PFAM: peptidase M20; peptidase dimerisation domain protein; SPTR: Xaa-His dipeptidase; TIGRFAM: dipeptidase; PFAM: Peptidase family M20/M25/M40; Peptidase dimerisation domain; TIGRFAM: dipeptidase, putative. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.663 |
| AEE95545.1 | pepT | Mahau_0329 | Mahau_0034 | Dipeptidase; COGs: COG0624 Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylase; InterPro IPR001261: IPR010964: IPR002933: IPR011650; KEGG: hor:Hore_08190 Xaa-His dipeptidase; PFAM: peptidase M20; peptidase dimerisation domain protein; SPTR: Xaa-His dipeptidase; TIGRFAM: dipeptidase; PFAM: Peptidase family M20/M25/M40; Peptidase dimerisation domain; TIGRFAM: dipeptidase, putative. | Peptidase T; Cleaves the N-terminal amino acid of tripeptides. Belongs to the peptidase M20B family. | 0.482 |
| AEE95960.1 | AEE95962.1 | Mahau_0761 | Mahau_0763 | KEGG: tit:Thit_0102 hypothetical protein; SPTR: Putative uncharacterized protein. | Peptidase M24; COGs: COG0006 Xaa-Pro aminopeptidase; InterPro IPR000587: IPR000994: IPR001131; KEGG: tte:TTE1280 Xaa-Pro aminopeptidase; PFAM: peptidase M24; creatinase; SPTR: Xaa-Pro aminopeptidase; PFAM: Metallopeptidase family M24; Creatinase/Prolidase N-terminal domain; Belongs to the peptidase M24B family. | 0.543 |
| AEE95960.1 | AEE95964.1 | Mahau_0761 | Mahau_0765 | KEGG: tit:Thit_0102 hypothetical protein; SPTR: Putative uncharacterized protein. | KEGG: aoe:Clos_1623 hypothetical protein; SPTR: Putative uncharacterized protein. | 0.418 |
| AEE95960.1 | aroQ | Mahau_0761 | Mahau_0762 | KEGG: tit:Thit_0102 hypothetical protein; SPTR: Putative uncharacterized protein. | 3-dehydroquinate dehydratase; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family. | 0.541 |
| AEE95960.1 | efp | Mahau_0761 | Mahau_0764 | KEGG: tit:Thit_0102 hypothetical protein; SPTR: Putative uncharacterized protein. | Translation elongation factor P (EF-P); Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase. | 0.508 |
| AEE95960.1 | topA | Mahau_0761 | Mahau_0844 | KEGG: tit:Thit_0102 hypothetical protein; SPTR: Putative uncharacterized protein. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.465 |
| AEE95962.1 | AEE95470.1 | Mahau_0763 | Mahau_0252 | Peptidase M24; COGs: COG0006 Xaa-Pro aminopeptidase; InterPro IPR000587: IPR000994: IPR001131; KEGG: tte:TTE1280 Xaa-Pro aminopeptidase; PFAM: peptidase M24; creatinase; SPTR: Xaa-Pro aminopeptidase; PFAM: Metallopeptidase family M24; Creatinase/Prolidase N-terminal domain; Belongs to the peptidase M24B family. | CMP/dCMP deaminase zinc-binding protein; COGs: COG2131 Deoxycytidylate deaminase; InterPro IPR002125: IPR016192: IPR016473; KEGG: chy:CHY_2556 putative ComE operon protein 2; PFAM: CMP/dCMP deaminase zinc-binding; SPTR: Putative comE operon protein 2; PFAM: Cytidine and deoxycytidylate deaminase zinc-binding region. | 0.664 |
| AEE95962.1 | AEE95545.1 | Mahau_0763 | Mahau_0329 | Peptidase M24; COGs: COG0006 Xaa-Pro aminopeptidase; InterPro IPR000587: IPR000994: IPR001131; KEGG: tte:TTE1280 Xaa-Pro aminopeptidase; PFAM: peptidase M24; creatinase; SPTR: Xaa-Pro aminopeptidase; PFAM: Metallopeptidase family M24; Creatinase/Prolidase N-terminal domain; Belongs to the peptidase M24B family. | Dipeptidase; COGs: COG0624 Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylase; InterPro IPR001261: IPR010964: IPR002933: IPR011650; KEGG: hor:Hore_08190 Xaa-His dipeptidase; PFAM: peptidase M20; peptidase dimerisation domain protein; SPTR: Xaa-His dipeptidase; TIGRFAM: dipeptidase; PFAM: Peptidase family M20/M25/M40; Peptidase dimerisation domain; TIGRFAM: dipeptidase, putative. | 0.537 |
| AEE95962.1 | AEE95960.1 | Mahau_0763 | Mahau_0761 | Peptidase M24; COGs: COG0006 Xaa-Pro aminopeptidase; InterPro IPR000587: IPR000994: IPR001131; KEGG: tte:TTE1280 Xaa-Pro aminopeptidase; PFAM: peptidase M24; creatinase; SPTR: Xaa-Pro aminopeptidase; PFAM: Metallopeptidase family M24; Creatinase/Prolidase N-terminal domain; Belongs to the peptidase M24B family. | KEGG: tit:Thit_0102 hypothetical protein; SPTR: Putative uncharacterized protein. | 0.543 |
| AEE95962.1 | AEE95964.1 | Mahau_0763 | Mahau_0765 | Peptidase M24; COGs: COG0006 Xaa-Pro aminopeptidase; InterPro IPR000587: IPR000994: IPR001131; KEGG: tte:TTE1280 Xaa-Pro aminopeptidase; PFAM: peptidase M24; creatinase; SPTR: Xaa-Pro aminopeptidase; PFAM: Metallopeptidase family M24; Creatinase/Prolidase N-terminal domain; Belongs to the peptidase M24B family. | KEGG: aoe:Clos_1623 hypothetical protein; SPTR: Putative uncharacterized protein. | 0.700 |
| AEE95962.1 | AEE96235.1 | Mahau_0763 | Mahau_1037 | Peptidase M24; COGs: COG0006 Xaa-Pro aminopeptidase; InterPro IPR000587: IPR000994: IPR001131; KEGG: tte:TTE1280 Xaa-Pro aminopeptidase; PFAM: peptidase M24; creatinase; SPTR: Xaa-Pro aminopeptidase; PFAM: Metallopeptidase family M24; Creatinase/Prolidase N-terminal domain; Belongs to the peptidase M24B family. | Phosphoesterase RecJ domain protein; COGs: COG0618 Exopolyphosphatase-related protein; InterPro IPR001667: IPR003156; KEGG: cth:Cthe_0989 phosphoesterase, RecJ-like protein; PFAM: phosphoesterase RecJ domain protein; phosphoesterase DHHA1; SPTR: Phosphoesterase, RecJ-like protein; PFAM: DHH family; DHHA1 domain. | 0.542 |
| AEE95962.1 | aroQ | Mahau_0763 | Mahau_0762 | Peptidase M24; COGs: COG0006 Xaa-Pro aminopeptidase; InterPro IPR000587: IPR000994: IPR001131; KEGG: tte:TTE1280 Xaa-Pro aminopeptidase; PFAM: peptidase M24; creatinase; SPTR: Xaa-Pro aminopeptidase; PFAM: Metallopeptidase family M24; Creatinase/Prolidase N-terminal domain; Belongs to the peptidase M24B family. | 3-dehydroquinate dehydratase; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family. | 0.977 |
| AEE95962.1 | efp | Mahau_0763 | Mahau_0764 | Peptidase M24; COGs: COG0006 Xaa-Pro aminopeptidase; InterPro IPR000587: IPR000994: IPR001131; KEGG: tte:TTE1280 Xaa-Pro aminopeptidase; PFAM: peptidase M24; creatinase; SPTR: Xaa-Pro aminopeptidase; PFAM: Metallopeptidase family M24; Creatinase/Prolidase N-terminal domain; Belongs to the peptidase M24B family. | Translation elongation factor P (EF-P); Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase. | 0.817 |
| AEE95962.1 | guaB | Mahau_0763 | Mahau_1974 | Peptidase M24; COGs: COG0006 Xaa-Pro aminopeptidase; InterPro IPR000587: IPR000994: IPR001131; KEGG: tte:TTE1280 Xaa-Pro aminopeptidase; PFAM: peptidase M24; creatinase; SPTR: Xaa-Pro aminopeptidase; PFAM: Metallopeptidase family M24; Creatinase/Prolidase N-terminal domain; Belongs to the peptidase M24B family. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.729 |
| AEE95962.1 | pepT | Mahau_0763 | Mahau_0034 | Peptidase M24; COGs: COG0006 Xaa-Pro aminopeptidase; InterPro IPR000587: IPR000994: IPR001131; KEGG: tte:TTE1280 Xaa-Pro aminopeptidase; PFAM: peptidase M24; creatinase; SPTR: Xaa-Pro aminopeptidase; PFAM: Metallopeptidase family M24; Creatinase/Prolidase N-terminal domain; Belongs to the peptidase M24B family. | Peptidase T; Cleaves the N-terminal amino acid of tripeptides. Belongs to the peptidase M20B family. | 0.617 |
| AEE95962.1 | topA | Mahau_0763 | Mahau_0844 | Peptidase M24; COGs: COG0006 Xaa-Pro aminopeptidase; InterPro IPR000587: IPR000994: IPR001131; KEGG: tte:TTE1280 Xaa-Pro aminopeptidase; PFAM: peptidase M24; creatinase; SPTR: Xaa-Pro aminopeptidase; PFAM: Metallopeptidase family M24; Creatinase/Prolidase N-terminal domain; Belongs to the peptidase M24B family. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.579 |
| AEE95964.1 | AEE95960.1 | Mahau_0765 | Mahau_0761 | KEGG: aoe:Clos_1623 hypothetical protein; SPTR: Putative uncharacterized protein. | KEGG: tit:Thit_0102 hypothetical protein; SPTR: Putative uncharacterized protein. | 0.418 |
