STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
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AEE95965.1ROK family protein; COGs: COG1940 Transcriptional regulator/sugar kinase; InterPro IPR001808: IPR000600; KEGG: bha:BH1094 transcriptional repressor of the xylose operon; PFAM: ROK family protein; SMART: regulatory protein Crp; SPTR: Transcriptional repressor of the xylose operon; PFAM: ROK family; MarR family. (406 aa)    
Predicted Functional Partners:
birA
biotin/acetyl-CoA-carboxylase ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family.
     
 0.664
AEE95260.1
FAD-dependent pyridine nucleotide-disulfide oxidoreductase; COGs: COG0446 NAD(FAD)-dependent dehydrogenase; InterPro IPR001763: IPR013027: IPR004099: IPR001455: IPR 003787; KEGG: cce:Ccel_1144 FAD-dependent pyridine nucleotide-disulphide oxidoreductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; pyridine nucleotide-disulphide oxidoreductase dimerisation region; Rhodanese domain protein; SirA-like domain-containing protein; DsrE family protein; SMART: Rhodanese domain protein; SPTR: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; PFAM: Pyridine nucle [...]
  
  
 0.646
AEE95333.1
NADH:flavin oxidoreductase/NADH oxidase; COGs: COG1902 NADH:flavin oxidoreductase Old Yellow Enzyme family; InterPro IPR001155: IPR013027: IPR000103; KEGG: mta:Moth_2056 NADH:flavin oxidoreductase/NADH oxidase; PFAM: NADH:flavin oxidoreductase/NADH oxidase; FAD-dependent pyridine nucleotide-disulphide oxidoreductase; SPTR: NADH:flavin oxidoreductase/NADH oxidase; PFAM: Pyridine nucleotide-disulphide oxidoreductase; NADH:flavin oxidoreductase / NADH oxidase family.
  
  
 0.628
AEE97123.1
NADH:flavin oxidoreductase/NADH oxidase; COGs: COG1902 NADH:flavin oxidoreductase Old Yellow Enzyme family; InterPro IPR001155: IPR001327: IPR013027: IPR000103; KEGG: tte:TTE2131 NADH:flavin oxidoreductase; PFAM: NADH:flavin oxidoreductase/NADH oxidase; FAD-dependent pyridine nucleotide-disulphide oxidoreductase; SPTR: NADH:flavin oxidoreductase/NADH oxidase; PFAM: Pyridine nucleotide-disulphide oxidoreductase; NADH:flavin oxidoreductase / NADH oxidase family.
  
  
 0.628
nadE
NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
  
  
 0.624
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
     
 0.613
AEE97529.1
COGs: COG0572 Uridine kinase; KEGG: tte:TTE1778 uridine kinase; SPTR: Phosphoribulokinase/uridine kinase; PFAM: Phosphoribulokinase / Uridine kinase family.
  
  
 0.596
AEE97484.1
FAD-dependent pyridine nucleotide-disulfide oxidoreductase; COGs: COG0446 NAD(FAD)-dependent dehydrogenase; InterPro IPR013027: IPR004099: IPR001763; KEGG: eat:EAT1b_1024 pyridine nucleotide-disulphide oxidoreductase dimerisation region; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; pyridine nucleotide-disulphide oxidoreductase dimerisation region; Rhodanese domain protein; SMART: Rhodanese domain protein; SPTR: Pyridine nucleotide-disulphide oxidoreductase dimerisation region; PFAM: Pyridine nucleotide-disulphide oxidoreductase; Rhodanese-like domain; Pyridine nuc [...]
  
  
 0.528
AEE95964.1
KEGG: aoe:Clos_1623 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.498
efp
Translation elongation factor P (EF-P); Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.
  
  
 0.478
Your Current Organism:
Mahella australiensis
NCBI taxonomy Id: 697281
Other names: M. australiensis 50-1 BON, Mahella australiensis 50-1 BON, Mahella australiensis DSM 15567, Mahella australiensis str. 50-1 BON, Mahella australiensis strain 50-1 BON
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