STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEE96130.1KEGG: cat:CA2559_06590 DNA-binding response regulator, LuxR family protein; SPTR: Putative uncharacterized protein. (56 aa)    
Predicted Functional Partners:
AEE96128.1
(p)ppGpp synthetase I, SpoT/RelA; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.
       0.678
AEE96129.1
Beta-lactamase domain protein; COGs: COG0491 Zn-dependent hydrolase including glyoxylase; KEGG: dae:Dtox_2285 beta-lactamase domain protein; SPTR: Metallo-beta-lactamase family protein; PFAM: Metallo-beta-lactamase superfamily.
       0.678
hisS
COGs: COG0124 Histidyl-tRNA synthetase; InterPro IPR004516: IPR002314: IPR004154: IPR006195: IPR 015807; KEGG: tmt:Tmath_1086 histidyl-tRNA synthetase; PFAM: tRNA synthetase class II (G H P and S); Anticodon-binding domain protein; PRIAM: Histidine--tRNA ligase; SPTR: Histidyl-tRNA synthetase; TIGRFAM: histidyl-tRNA synthetase; PFAM: Anticodon binding domain; tRNA synthetase class II core domain (G, H, P, S and T); TIGRFAM: histidyl-tRNA synthetase.
       0.586
apt
Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
       0.580
aspS
aspartyl-tRNA synthetase; Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp- AMP and then transferred to the acceptor end of tRNA(Asp). Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
       0.570
AEE96126.1
single-stranded-DNA-specific exonuclease RecJ; COGs: COG0608 Single-stranded DNA-specific exonuclease; InterPro IPR001667: IPR003156: IPR004610; KEGG: amt:Amet_2351 single-stranded-DNA-specific exonuclease RecJ; PFAM: phosphoesterase RecJ domain protein; phosphoesterase DHHA1; SPTR: Single-stranded-DNA-specific exonuclease RecJ; TIGRFAM: single-stranded-DNA-specific exonuclease RecJ; PFAM: DHHA1 domain; DHH family; TIGRFAM: single-stranded-DNA-specific exonuclease RecJ.
       0.544
AEE96123.1
Radical SAM domain protein; COGs: COG0641 Arylsulfatase regulator (Fe-S oxidoreductase); InterPro IPR007197: IPR000385; KEGG: aoe:Clos_1718 radical SAM domain-containing protein; PFAM: Radical SAM domain protein; SPTR: Radical SAM domain protein; PFAM: Radical SAM superfamily.
       0.466
secD
Protein-export membrane protein SecD; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.
       0.466
secF
Protein translocase subunit secF; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.
       0.466
Your Current Organism:
Mahella australiensis
NCBI taxonomy Id: 697281
Other names: M. australiensis 50-1 BON, Mahella australiensis 50-1 BON, Mahella australiensis DSM 15567, Mahella australiensis str. 50-1 BON, Mahella australiensis strain 50-1 BON
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.